RNA VIRUSES

1. MYXOVIRUSES

2. PARAMYXOVIRUSES

3. RHABDOVIRUSES

4. REOVIRUSES

5. PICORNAVIRUSES

6. TOGAVIRUSES

7. FLAVIVIRUSES

8. FILOVIRUSES

9. DELTAVIRIDAE

10. RETROVIRIDAE

RNA Viruses

INFLUENZA VIRUS

Myxoviruses Examples

MUMPS VIRUS

MEASLES VIRUS

Paramyxoviruses Examples

RABIES VIRUS

Rhabdoviruses Examples

ROTAVIRUSES

Reoviruses Examples

POLIOVIRUS

RHINOVIRUS

HEPATITIS A VIRUS (HAV)

Picornaviruses Examples

RUBELLA

Togaviruses Examples

YELLOW FEVER VIRUS

HCV

DENGUE VIRUS

Flaviviruses Examples

EBOLA VIRUS

Filoviruses Examples

HDV

Deltaviridae Examples

HUMAN T-CELL LEUKEMIA (HTLV-1)

HUMAN IMMUNODEFICIENCY VIRUS (HIV)

Retroviridae Examples

COAT • Enveloped.

CAPSOMERES • Helical Symmetric Capsid.

NUCLEIC ACID • Segmented RNA - (+) ss RNA.

INFLUENZA VIRUS

Coat -

Capsomeres -

Nucleic Acid -

HEMAGGLUTININ and NEURAMINIDASE

spikes that project from the envelope in Influenza Virus

LINING the UPPER RESPIRATORY

TRACT

Influenza Virus only multiplies in the cells ____

Absorption of TOXIC breakdown products from the DYING

CELLS on the RESPIRATORY Epithelium.

The Constitutional Symptoms of INFLUENZA are probably

brought about by:

INFLUENZA VIRUS

Capable of Extensive ANTIGENIC VARIATIONS

These NEW Antigenic Types can cause PANDEMICS

ANTIGENIC VARIATIONS

Production of new types of viruses which the human

population does NOT have effective immunity agains

COAT • Enveloped.

CAPSOMERES • Helical Capsid.

NUCLEIC ACID • (-) ss RNA.

Mumps Virus

Coat -

Capsomeres -

Nucleic Acid -

PAROTID and SUBMAXILLARY SALIVARY GLANDS.

Mumps Virus infection in children produces characteristic swelling of ___

MUMPS VIRUS

The disease can have - NEUROLOGICAL COMPLICATIONS.

o EXAMPLE: Meningitis - especially in Adults.

COAT • Enveloped.

CAPSOMERES • Helical Capsid.

NUCLEIC ACID • (-) ss RNA.

Measles Virus

Coat -

Capsomeres -

Nucleic Acid -

MEASLES VIRUS

• Very COMMON - Childhood Fever.

• IMMUNITY is LIFELONG.

• SECOND ATTACKS are very RARE

COAT • Enveloped.

CAPSOMERES • Helical Capsid.

NUCLEIC ACID • (-) ss RNA.

SHAPE • Bullet-shaped.

Rabies Virus

Coat -

Capsomeres -

Nucleic Acid -

Shape -

RABIES VIRUS

• very wide host range, infecting all mammals: dogs,cats and cattle are particularly susceptible

• incubation period is extremely varied, ranging from 6 days up to 1 year

FATAL ENCEPHALITIS

Rabies virus remains LOCALIZED at the wound site of entry for a while before passing along nerve fibers to central nervous system, producing a fatal ____

CAPSOMERES • Inner Core is surrounded by Two Concentric Icosahedral Shells.

NUCLEIC ACID • Segmented ds RNA.

Rotaviruses

Capsomeres -

Nucleic Acid -

ROTAVIRUSES

• Very COMMON cause of GASTROENTERITIS for infants

• SPREADS THROUGH:

o Poor Water Supplies.

o Standards of General Hygiene are Low

• In developing countries, it is responsible for about a MILLION

DEATHS each year.

PICORNAVIRUSES

smallest viruses

COAT • Naked.

CAPSOMERES • Icosahedral - Polyhedral.

NUCLEIC ACID • (+) ss RNA.

Polioviruses

Coat -

Capsomeres -

Nucleic Acid -

POLIOVIRUSES

• One of the groups of

ENTEROVIRUSES -

o Common in the GUT of humans.

• ASYMPTOMATIC 95% of the time.

LYMPHOID TISSUE of the

Alimentary Tract