muscarinic agonist-exam 1

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Last updated 9:05 PM on 6/11/26
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12 Terms

1
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cholinergic drug classes

muscarinic agonist, muscarinic antagonist, cholinesterase inhibitor

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muscarinic agonist

parasympoathicmimetics, bind to muscarinic receptor and mimic parasympathetic NS

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muscarinic agonist drug protypes

bethanechol and pilocarpine

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bethanechol MOA

stimulates muscarinic receptor to allow bladder to empty

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bethanechol indication

treats urinary retention and conditions

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bethanechol pharmacokinetics

PO, not absorbed well, given 3-4 x daily

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bethanechol adverse effects

hypotension and bradycardia (M2), excessive GI effects and bronchoconstriction (M3)

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pilocarpine MOA

binds to smooth muscle and makes it contract

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pilocarpine indication

glaucoma or xerostomia

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pilocarpine pharmacokinetics

glaucoma: gel on eye/eyedrops

xerstomia: orally

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pilocarpine adverse effects

increased GI motility, effects worse when PO

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teaching point for pilocarpine

it should not be taken with fatty foods orally, limited research for use in pregnant/lactating women and children