MHD H4P Lab 2 - Skin

types of epithelial cells (4)

keratinocytes
melanocytes
merkel cells
langerhans cells

layers of epidermis

Cancel Lab Get Some Beer

corneum
lucidum
granulosum
spinosum
basale

thick skin is also known as _____ skin and lacks _____ glands and has increased _____ glands

acral
sebaceous
eccrine

thin skin does not have stratum _____

lucidum

from basal cell to cornified cell (desquamation) takes about _____ days

25

epidermal cell to cell adherence

_____: tight junctions that prevent diffusion across cells

zona occludens

epidermal cell to cell adherence

_____: Ca2+ dependent cadherins that connect to actin

zona adherins

epidermal cell to cell adherence

_____: made of desmosomes

macula densa

epidermal cell to cell adherence

_____: communication for electric/metabolic function

gap junctions

epidermal cell to cell adherence

_____: connect basal keratinocytes to basement membrane

hemidesmosomes

desmosomes are _____

intercellular bridges

_____: clearish cells in basal layer of epidermis with dark nuclei, ratio of 1:10

melanocytes

_____: dendritic cells of the epidermis, sit in the mid-spinous, not visible by light microscopy

langerhan's cells

_____: located in the stratum basale, also not visible by light microscopy, receptor cells that establish synaptic contacts with sensory nerves and contain granules of neurotransmitters

merkel cells

basement membrane: _____ contains collagen types XVII, XIII, and laminin 5 & 6

lamina lucida

basement membrane: _____ contains collagen type VII

lamina densa

_____ attach the basement membrane to the dermis, hooking onto collagen VII and I

anchoring fibrils

_____: includes dermal papilla which project into the epidermis (increases contact area preventing epidermal detachment)

papillary dermis

_____ dermis: area between the papillary dermis and subcuti

reticular

_____ dermis contains capillaries, free nerve endings and meissner's corpuscles (encapsulated sensory receptors)

papillary

dermis is composed of two major types of fibers:

type I collagen
elastic fibers

_____: simple branched acinar glands that empty "sebum" into hair follicle via holocrine secretion

sebaceous glands

_____: merocrine sweat glands that release to adjust body temperature

eccrine glands

eccrine gland cell types (3 total)

_____ cells: pyramid shaped with secretory granules, line lumen of tubule

dark

eccrine gland cell types (3 total)

_____ cells: located toward basement membrane

clear

eccrine gland cell types (3 total)

_____ cells: spindle shaped contractile cell

myoepithelial

_____: glands with large lumens and ducts that empty onto superficial regions of hair follicle, release product by shedding part of cytoplasm, influenced by hormones (sexual scent glands)

apocrine glands

_____: area deep to the dermis (includes hypodermis), that includes loose connective tissue containing adipose tissue, nerves, sensory receptors, arteries and veins; provides flexible attachment to the underlying muscle and fascia

subcutis