ALL DRUGS (name and class/use)

Acepromazine

Phenothiazine - dopamine-2 receptor antagonist, smooth muscle relaxant, anxiolytic, vasodilation, anti-emetic

Mild to moderate sedation

Onset - 20-40 minutes

Duration - 4-6 hours

Equine - fractious horses, exercise-induced exertional rhabdomyolitis

Smallies - mitral valve disease, BOAS, laryngeal paralysis, upper respiratory tract disease, feline urethral spasm, tetanus

In combination with alpha-2 agonists for a background calming effect

Side effects - ↓ contractility → hypotension

Acetazolamide

Carbonic anhydrase inhibitor - weak diuretic

Equine - glaucoma

Smallies - Chiari-like malformation, Metabolic alkalosis

Afoxolaner

Isoxazoline - GABA and glutamate receptor antagonist → paralysis of parasite

Fleas, ticks, mites, Babesia

Aglepristone

Progesterone receptor antagonist

Smallies - pyometra, abortion <45 days

Albendazole

1-BZ anthelmintic (benzimidazole)

Farm - Fasciola spp, Trichinella spp, Echinococcus spp

Carbamizole

Thioureylene - inhibits thyroid hormone synthesis

Levothyroxine

Synthetic T4

Liothyronine

Synthetic T3

Trilostane

Adrenal steroid synthesis inhibitor (Cushing's)

Pergolide

Dopamine agonist (PPID)

Albuterol

B2 receptor agonist - bronchodilator

Altrenogest

Progesterone receptor agonist

Amiloride

Potassium-sparing diuretic

Amitraz

Ectoparasiticide - treats demodectic mange

Atropine

Parasympatholytic - positive inotrope

DDAVP

Synthetic ADH

Amlodipine

Calcium channel blocker (more active in smooth muscle) - antihypertensive

Amphotericin B

Anti-fungal - used for severe systemic mycosis

Apomorphine

Dopamine agonist - emetic

Aspirin

NSAID - COX-1 inhibitor; anticoagulant

Atenolol

B1 antagonist - class II antidysrhythmic

Can be used for aortic stenosis - negative chonotrope, negative inotrope

Azathioprine

Prurine synthesis inhibitor - immunosuppressive

Benazepril

ACE inhibitor - antihypertensive

Betaxolol

Beta-blocker - treats glaucoma

Bromhexine HCl

Mucolytic (ineffective in presence of infection/inflammation)

Butorphanol

Opioid - mu antagonist, kappa agonist

Butylscopolamine

M1-muscarinic acetylcholine receptor inhibitor - anti-spasmodic

Cabergoline

Prolactin inhibitor

Calcium acetate

Phosphate binder - prevents GI phosphate absorption

Ciclosporin

Immunosuppressive (inhibits IL-2 by blocking calcineurin activation)

Cimetidine

Histamine blocker (H2 - proton pump blocker)

Clenbuterol

B2 receptor agonist - bronchodilator for horses

Clotrimazole

Imidazole (ear drop)

Posaconazole

Imidazole - topical in dogs and cats

Codeine

Full opioid agonist

Colchicine

Antifibrotic

Cypermethrin

Synthetic pyrethroid (flies, lice, ticks)

Cyproheptadine

Antihistamine + anticholinergic/antiserotonergic/anaesthetic (appetite stimulant)

Cyromazine

Chitin inhibitor

Dantrolene

Ryanodine receptor antagonist (prevents skeletal muscle contraction)

Delmadinone acetate

Androgen receptor antagonist

Deltamethrin

Synthetic pyrethroid (flies, lice, ticks)

Depsipeptide

Anti-nematode for cats

Deslorelin

GnRH agonist (used in implants)

Detomidine

Alpha-2 agonist - sedative

Dexamethasone

Glucocorticoid

Diazepam

Benzodiazepine (longer-acting)

Diazinon

Organophosphate (sheep dip)

DDT (dichlorodiphenyltrichloroethane)

Organochlorine (banned)

Dicyclanil

Chitin inhibitor

Diflubenzuron

Chitin inhibitor

Digoxin

Cardiac glycoside - vagomimetic (class V antidysrhythmic)

Diltiazem

Calcium channel blocker (class IV antidysrhythmic)

Diphenhydramine

Anti-histamine (H1 - anti-emetic)

Diphenoxylate

Synthetic opiate (anti-diarrhoeal)

Dipyrone

NSAID - non-selective

Dobutamine

B1 agonist - positive inotrope

Docusate

Surfactant laxative

Doramectin

Macrocyclic lactone (mites, lice, bots, warbles)

Dorquantel

Spiroindole (5-SI anthelmintic)

Doxapram

Respiratory stimulant

Doxycycline

Broad-spectrum tetracycline

Ephedrine

Sympathomimetic

Estriol

Oestrogen receptor agonist (treatment of urethral sphincter incompetence in spayed bitches)

Eprinomectin

Macrocyclic lactone (mites, lice, bots, warbles)

Fenbendazole

Benzimidazole

Fipronil

Phenylpyrazole (fleas, ticks)

Firocoxib

NSAID - COX-2 inhibitor

Flubendazole

Benzimidazole

Fluconazole

Triazole

Flunixin meglumine

NSAID (long-acting)

Fluralaner

Isoxazoline (fleas, ticks, mites)

Griseofulvin

Anti-fungal

Guaifenesin

Expectorant (increases vagal tone)

Furosemide

Loop diuretic

Human recombinant erythropoietin

Erythropoietin receptor agonist

Hydralazine

Vasodilator (IP3 inhibitor - reduces Ca2+ release from SR)

Hydrochlorothiazide

Diuretic (inhibits ion reabsorption in proximal DCT)

Imidacloprid

Neonicotinoid (fleas, biting lice)

Imiquimod

Immune stimulant - Langerhans cells

Ipatropium

Anticholinergic - bronchodilator

Itraconazole

Triazole

Ispaghula

Bulk laxative

Ivermectin

Macrocyclic lactone (collies sensitive) (mites, lice, bots, warbles)

Kaolin-pectin

Protectant/adsorbant anti-diarrhoeal

Ketoconazole

Imidazole

Lactulose

Osmotic cathartic (reduces blood ammonia)

Leflunomide

Immunosuppressive (inhibits lymphocyte synthesis)

Levamisole

Imidathiazole/tetrahydropyrimadine

Lidocaine

Amide (local anaesthetic, class 1b antidysrhythmic)

Lime sulphur

Anti-fungal (dip used to treat dermatophytosis in cats)

Liposomal clodronate

Immunosuppressive (treatment of IMHA/IMTP)

Lokivetmab

Immunosuppressive (anti-IL-31)

Loperamide

Opiate - anti-diarrhoeal

Lotilaner

Isoxazoline (fleas, ticks, mites)

Mannitol

Osmotic diuretic

Lufenuron

Chitin inhibitor

Maropitant

NK-1 receptor blocker (anti-emetic)

Meloxicam

NSAID - COX-2 inhibitor

Mebendazole

Benzimidazole