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discuss the four primary functions of estrogen in female reproductive physiology
maturation and maintenance of the female reproductive system
establishment of female secondary sexual characteristics
ova maturation and release
transport of sperm from the vagina to the site of fertilization in the oviduct
summarize the two principal functions of the female ovaries
produce estrogen and progesterone
summarize the most important functions of progesterone in the female reproductive cycle.
prepare a suitable environment for nourishing the developing embryo and fetus
where does oogenesis occur?
outermost layer of the ovaries
discuss the first part of oogenesis regarding the oogonia turning into primary oocyte
oogonia (undifferentiated primordial sex cells) divide mitotically to produce diploid primary oocyte (surrounded by a primary follicle). most follicles do NOT mature to ova or ovulate
discuss the process of oogenesis from puberty to menopause where primary oocytes (follicles) develop
primary oocytes go through 1st meiotic division just before ovulation forming a secondary oocyte and a smaller first polar body
discuss what happens during oogenesis when the secondary oocyte is ovulated and potentially fertilized
if fertilized a second meiotic division occurs, this produces a secondary polar body (haploid) and a haploid mature ovum. if fertilized unites w/ haploid sperm cell
primary different between follicular and literal phases of the ovarian cycle
follicular = low hormone levels
literal = high hormone levels
purpose of follicular phase
mature granulosa cells to follicles
discuss the three major steps of the follicular phase
granulosa cells of some primary follicles proliferate
the oocyte inside of each follicle is enlarging
theca cells in the follicle secrete increased amounts of estrogen which circulates throughout the body; one follicle grows rapidly, maturing in 14 days for ovulation
how long does it take the follicle to mature? what happens once it reaches maturity?
14 days; released from ovary → oviduct where it may or may not be fertilized
define/describe ovulation
the follicle ruptures to release the oocyte from the ovary
what is the corpus luteum?
the follicle left behind in the ovary after it loses its sex cell by ovulation; controls last 14 days of cycle; secretes progesterone and estrogen
the ovarian cycle is regulated by complex hormonal interactions. list the 4 key hormones involved.
FSH, LH, estrogen, and progesterone.
the follicular phase starts with a rise in which hormone?
FSH
the rise in FSH in the follicular phase signals the ovarian follicle to what?
secrete more estrogen
a rise in estrogen by the ovarian follicle inhibits the secretion of what hormone?
FSH; which steadily declines as follicular phase proceeds
after FSH secretion is inhibited, what hormone begins to rise? what does this trigger?
LH rises in the follicular phase, peak triggers ovulation
ovulation triggers two things, what are they?
estrogen levels decrease
mature follicle is converted to a corpus luteum
what hormone(S) is secreted by the corpus luteum during the luteal phase?
progesterone and estrogen
the release of progesterone from the corpus luteum during the luteal phase does what?
progesterone inhibits the release of FSH and LH
what happens after the drop of FSH and LH in the luteal phase?
low LH degenerates corpus luteum and progesterone declines; FSH can start to rise again, cycle repeats.
there are concurrent changes in the uterus with the cyclical changes in the hormones during the female cycle. describe what happens in the beginning of the cycle.
there are concurrent changes in the uterus with the cyclical changes in the hormones during the female cycle. describe what happens in the proliferative phase of the cycle.
there are concurrent changes in the uterus with the cyclical changes in the hormones during the female cycle. describe what happens in the secretory phase of the cycle.
there are concurrent changes in the uterus with the cyclical changes in the hormones during the female cycle. describe what happens in the end of the cycle.
what is menopause?
what are fimbriae? describe their function
for how long can sperm survive in the female reproductive tract
what is an ectopic pregnancy?
briefly describe how sperm migration is “helped” by the female reproductive tract
explain the function of acrosomal enzymes in the context of conception
describe the zygote and what it forms? location?
describe the morula and what it forms. function? location?
blastocyst
describe the blastocyst and its layers
summarize the function of the trophoblast
what is the function of the placenta?
list the 5 placental hormones that play an important role in the maintenance of pregnancy.
describe human chorionic gonadotropin (hCG) hormone
describe estrogen function
describe progesterone function (placenta)
describe relaxin function (placenta)
describe placental PTHrp function (placenta)
summarize the role of fetal CRH in preparation for parturition
describe the 3 stage process of labor
cervical dilation
birth of the baby
placental birth; series of secondary contractions separate the placenta from the myometrium and expels it
list the 4 hormones involved in lactation
estrogen, progesterone, prolactin, oxytocin
estrogen function lactation
promotes extensive duct development in breasts
progesterone function lactation
stimulates alveolar lobular development
prolactin function lactation
contributes to mammary gland development and milk secretion
oxytocin function lactation
induces milk ejection
discuss some of the advantages breast feeding offers to both mom and baby
release oxytocin which speeds up the process of the uterus returning to its normal size
offers immune cells to the infant