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DM vs DI vs SIADH (Core Concept)
DM is sugar problem; DI is water leaving; SIADH is water staying.
Memory trick for DM, DI, and SIADH
DM = Maple Syrup. DI = Desert Inside. SIADH = Sponge Syndrome.
Fluid Volume Deficit conditions
DM, DI, DKA, and HHS.
Fluid Volume Excess condition
SIADH.
NCLEX Priority Assessment for fluid balance
Assess blood pressure, heart rate, mental status, and urine output.
What are the 3 Ps of Diabetes Mellitus?
Polyuria, polydipsia, and polyphagia.
Cause of the 3 Ps in Diabetes Mellitus
Glucose remains in bloodstream while cells are starving.
Type 1 Diabetes (Core Concept)
Autoimmune destruction of beta cells; little to no insulin production.
Type 2 Diabetes (Core Concept)
Insulin resistance and progressive loss of insulin production.
Memory trick for Type 1 vs Type 2 Diabetes
Type 1 = No insulin factory. Type 2 = Factory workers ignore insulin.
Type 2 Diabetes first-line medication
Metformin.
Metformin side effects and contraindications and use
GI upset, diarrhea, rare lactic acidosis; hold for severe kidney dysfunction. decreases insulin liver production in type 2
SGLT2 Inhibitors suffix and mechanism
Ending: -flozin. Mechanism: Flush sugar through the urine. type 2
SGLT2 Inhibitors risks
UTI, genital fungal infections, and dehydration.
GLP-1 Receptor Agonists suffix and memory trick
Ending: -tide. Memory: Get Lean Patients (promotes weight loss). type 2
NCLEX rule for Rapid Acting Insulin
Give with meals. Hold if meal tray is delayed.
Regular Insulin key fact and memory trick
Can be given IV. Memory: Regular Runs IV.
NPH Insulin key facts
Intermediate acting, cloudy suspension, cannot be given IV.
Long Acting Insulin rule
Glargine, Detemir, Degludec. Do not mix Glargine with other insulins.
Insulin mixing order
Clear before cloudy. Draw up Regular before NPH (RN).
Peak Insulin Action risk
Hypoglycemia is most likely to occur during insulin peak.
Hypoglycemia symptoms memory trick
Cold and clammy needs candy (sweating, tremors, confusion, tachycardia).
Hypoglycemia Treatment (Conscious Patient)
15-15 Rule: 15 g rapid carbohydrates, recheck in 15 minutes.
Hypoglycemia Treatment (Unconscious Patient)
Glucagon IM/SQ (no IV access) or Dextrose IV (IV access available).
Hyperglycemia symptoms memory trick
Hot and dry needs fluids (dehydration, polyuria, polydipsia).
Exercise effect on insulin
Increases insulin sensitivity; acts like a free insulin shot.
Diabetes Sick Day Rules
Continue insulin, check glucose frequently, drink fluids, monitor ketones.
DKA description and memory trick
Burning furniture for heat (burning fat for energy, producing ketones).
Hallmark findings of DKA
Dehydration, ketones, acidosis, Kussmaul respirations, fruity breath, abdominal pain.
Mnemonic for Kussmaul respirations
Blowing out the fire (blowing off acid rapidly).
DKA Treatment Priority
Fill the tank then fix the engine (IV fluids first, then IV insulin).
HHS description and priority treatment
Sahara Desert Syndrome (extreme dehydration). Priority: Aggressive fluid replacement.
DKA vs HHS comparison
DKA: Type 1, ketones, acidosis. HHS: Type 2, no ketones, higher mortality.
Diabetic Foot Care key rule
LOOK Before You WALK. Inspect daily, wear shoes, never go barefoot.
A1C Benchmarks
Normal: <5.7%. Prediabetes: 5.7-6.4%. Diabetes: 6.5% or greater.
NCLEX Priority Rule: Glucose vs Acidosis
Low sugar kills faster than high sugar.
Rapid insulin think:
LAG, Lispro, Aspart, Glusimine
Rapid insulin (timing)
LAG, onset:15 peak1hr duration 3hrs
Short regular insulin think
R. Novolin R, Atropid R, Humulin R
Short (reg) insulin timing
R. onset: 30 min, peak:2-4hr, duration:6hrs
Intermediate think
N. NPH, Novalin N, Humulin N
intermediate timing
N. onset: 60 min, peak:4-8hrs, duration: 12hrs
Long acting think
GlaDe (glargine, detemir, degludec) L. Levemir, Lantus, Lente
Long acting timing
L. onset:120min, Peak: NONE, duration: 24hrs