Top 200 Exam 3

Xarelto

rivaroxaban

Crestor

rosuvastatin

Lipitor

atorvastatin

Pravachol

pravastatin

Tricor

fenofibrate

Zetia

Ezetimibe

Depakote

divalproex

Dilantin

Phenytoin

Keppra

levetiracetam

Lamictal

lamotrigine

Neurotin

Gabapentin

Gralise

Gabapentin

Tegretol

carbamazepine

Topomax

topiramate

Vimpat

lancosamide

Ambien

zolpidem

Zolpimist

zolpidem

Edular

Zolpidem

Belsomra

suvorexant

Lunesta

eszopiclone

Provigil

modafinil

Nuvigil

armodfinil

Cymbalta

duloxetine

Desyrel

trazodone

Effexor

venlafaxine

Elvail

amitriptyline

Lexapro

escitalopram

Paxil

paroxetine

Prozac

fluoxetine

Remeron

mirtazapine

Wellbutrin

bupropion

Lithonate

lithium carbonate

Zoloft

sertraline

Abilify

aripiprazole

Clozaril

clozapine

Lithotabs

lithium carbonate

Risperdal

risperidone

Seroquel

olanzapine

Adderall

amphetamine/dextroamphetamine

concerta

methylphenidate

Ritilian

Methylphenidate

Strattera

Atomoxetine

Vyvanse

lisdexamfetamine

Ativan

lorazepam

Buspar

Buspirone

Valium

Diazepam

Xanax

Alprazolam

Augmentin

Amox/clav

Unasyn

Amp/Sulbactam

Bactrim

sulfamethoxazole/trimethoprim

Sulfatrim

sulfamethoxazole/trimethoprim

Centany

Mupirocin

Cipro

Ciprofloxacin

inhibits platelet activation and fibrin clot formation via direct, selective and reversible inhibition of factor Xa

rivaroxaban

inhibits HMG-CoA reductase that decreases production of cholesterol

rosuvastatin

HMG-CoA reductase inhibitor

\-aka the RLS in synthesis

atorvasatin

HMG-CoA reductase inhibitor

pravastatin

activates PPAR alpha > increased

\n activates PPAR alpha > increased lipoprotein lipase

inhibits absorption of cholesterol in small intestine (jejunum)

Ezetimbie

increased availability of GABA, blocks voltage gated sodium channels

divalproex

increasing efflux/decreasing influx of sodium ions in motor cortex

phenytoin sodium

inhibits release of glutamate voltage gated sodium channels, which stabilizes neuronal membranes

lamotrigine

Unknown MOA

Levetiracetam

structurally related to GABA, targets Ca channel voltage

gabapentin

GABA agonist

Phenobarbital

enhancement of Na channel inactivation by reducing high frequency repetitive firing of action potentials and action on synaptic transmission

carbamazepine

blocks neuronal voltage gated dependent sodium channels, enhances GABA A activity

Topiramate

stabilizes hyperexcitability neuronal membranes and inhibits repetitive neuronal firing enhancing slow inactivation of sodium channels

lacosamide

enhances the activity of inhibitory neurotransmitter GABA, via selective antagonism at Benzoreceptor BZ1

zolpidem

blocks the binding of wake-promoting neuropeptides orecxin A and B ti receptors OX1R and OX2R

suvorexant

may interact with GABA receptor complexes at allosteric benzo receptors

eszopicolone

Unknown MOA

Modafanil

Unknown MOA

Armodafinil

inhibitor of neuronal serotonin and NE reuptake and a weak inhibitor of DA reuptake

duloxetine

inhibits reuptake of serotonin and acts as 5HTA receptor antagonist and induces significant changes in 5HT presynaptic receptor adrenoreceptors

trazodone

potent inhibitor of neuronal serotonin and NE reuptake and weak inhibitor of DA reuptake

venlafaxine

inhibits reuptake of serotonin and NE in CNS

Amitriptyline

inhibits presynaptic serotonin reuptake: increased serotonin in the synaptic cleft

escitalopram

selective serotonin reuptake inhibitor

paroxetine

inhibits presynaptic serotonin reuptake : increased serotinin in synaptic cleft

fluoxetine

TCA : central alpha 2 antagonist and 5HT2/3 antagonist, histamine and peripheral alpha

mirtazepine

DA and NE reuptake inhibitor

Bupriopion

\n SSRI

sertraline

\-5HT1A and D2 partial agonist

\-5HT2A antagonist

Aripiprazole

\-D2 antagonist

\-5HT2A antagonist

clozapine

Unknown MOA

Lithium

\-D2 antagonist

\-5HT2A antagonist

risperidone

\-D2 and D1 antagonist

\-5HT2c and 1A antagonist

quetiapine

\-5HT2a/2c

\-5HT6

\-D1-D4

all antagonism

olanzapine

increase NE and DA by inhibiting reuptake

adderall

increase NE and DA by inhibiting reuptake

ritilan

increase NE and DA by inhibiting reuptake

vyvanse

inhibits NE reuptake (NO affect on DA)

atomoxetine

GABA A agonist by binding allosterically and increasing the frequency of opening so more Cl influx

xanax

GABA A agonist by binding allosterically and increasing the frequency of opening so more Cl influx

lorazepam

GABA A agonist by binding allosterically and increasing the frequency of opening so more Cl influx

diazepam

\-5HTa1 agonist 5HT2 and D2

buspirone

aminopenacillin + BLI : inhibits bacterial cell wall synthesis

Unasyn

aminopenacillin + BLI : inhibits bacterial cell wall synthesis

Augmentin

interferes with folic acid synthesis

Bactrim