Ks' ALAT UNIT 1 (Chap 1-4) Practice Exam Questions

The Primary goal of laboratory animal science is to:

Ensure humane care & valid scientific results

Which principle encourages alternatives to animal use?

Replacement

Which entity enforces the Animal Welfare act?

USDA

Which animals are excluded from AWA coverage?

Purpose-bred mice

The IACUC is responsible for:

Reviewing animal use protocols

What does “Refinement” involve?

Reducing pain & distress

PHS Policy applies to:

All vertebrates in funded research

OLAW oversees compliance with:

PHS Policy

Poor animal care can result in:

Invalid results

The Guide provides:

Care recommendations

Which is an ALAT responsibility?

Daily animal care

Reduction refers to:

Using fewer animals

Which organizations conducts facility inspections internally?

IACUC

AWA regulations focus on:

Animal housing & care

Which species is covered under AWA?

Guinea pigs

Replacement includes:

Using computer models

Who ensures institutions follow PHS policy?

OLAW

Which document is required under PHS Policy?

The Guide

Animal stress affects:

Research outcomes

Which Grp can suspend noncompliant research?

IACUC

AWA is a:

Federal law

Which is not a rule of the IACUC?

Law enforcement

Refinement includes:

Better anesthesia

ALATs should report:

Health concerns

Which is covered under PHS policy?

All vertebrates

The Guide is used for:

Recommendations

Which is an example of Reduction?

Better design

Which agency enforces AWA?

USDA

Which species is NOT covered by AWA?

Mouse (lab-bred)

Animal welfare emphasizes:

Humane treatment

Which is a technician duty?

Monitor animals

PHS policy requires:

IACUC involvement

OLAW stands for:

Office of laboratory animal welfare

Which principle reduces pain?

Refinement

IACUC reviews:

Animal protocols

Which is an alternative method?

Computer simulation

The Guide addresses:

All of what is mentioned

Ethical use requires:

Justification

Which agency is tied to PHS?

OLAW

Which is not part of the 3 Rs?

Regulation

(T/F) IACUC reviews & approves animal protocols

T

(T/F) AWA covers all vertebrate animals

F

(T/F) PHS policy applies only to mammals

F

(T/F) Replacement means using alternatives

T

(T/F) Poor care can affect data

T

(T/F) OLAW enforces AWA

F

(T/F) Refinement reduces pain/distress

T

(T/F) ALATs are responsible for daily care

T

(T/F) The Guide is legally enforceable like a law

F

(T/F) Reduction minimizes animal numbers

T

A researcher switches to cell cultures instead of animals

Replacement

An experiment uses improved anesthesia to reduce pain

Refinement

A study redesign reduces the number of animals needed

Reduction

A facility fails sanitation standards. Who addresses it first internally?

IACUC

NIH-funded fish study—what applies?

PHS policy

What is the primary purpose of the Animal Welfare Act (AWA)?

To ensure humane treatment of certain research animals

Which agency enforces the Animal Welfare Act?

USDA

Which species are NOT covered by the Animal Welfare Act?

Purpose-bred mice

Public Health Services (PHS) Policy applies to:

All vertebrate animals used in PHS-funded research

The Guide for the Care & Use of Laboratory Animals provides:

Standards for Laboratory animal care & use

AAALAC International accreditation is:

Voluntary

The “3Rs” were developed by:

Russell & Burch

Which of the following is an example of Replacement?

Using computer simulations instead of animals

Which of the following is an example of Reduction?

Better statistical planning

Which of the following is an example of Refinement?

Using proper pain relief

The IACUC is responsible for:

Reviewing animal use protocols

Which member is required on the IACUC?

Community member is not affiliated with the institution

The IACUC must inspect animal facilities at least:

Every 6 months

Which individual has authority over veterinary care in an animal program?

Attending Veterinarian

Which is considered a sign of pain or distress in animal?

Lethargy

A humane endpoint is:

The point at which unnecessary suffering is prevented

Which organization publishes euthanasia guidelines commonly used in research

AVMA

Which method is commonly used for rodent euthanasia when approved?

CO2 inhalation

Which of the following is considered permanent animal identification?

Microchip

Why is accurate record keeping important?

It supports compliance & animal health monitoring

Which statement about AAALAC is TRUE?

It promotes high standards of animal care

Which of the following is part of occupational health and safety?

Wearing proper PPE

Which of the following is a zoonotic hazard?

Diseases transmitted between animals & humans

Procedures causing more than slight pain generally require:

Analgesia or anesthesia unless scientifically justified

Environmental enrichment is used to:

Improve psychological well-being

Which statement abt PHS Policy is true?

It applies to institutions receiving PHS funding

Which is an example of temporary identifciation?

Cage card

The goal of euthanasia is to:

Minimize pain & distress

Which of the following best describes a Culture of Care?

A commitment to animal welfare, ethics, and responsibility

(T/F) Purpose-bred rats are covered under the Animal Welfare Act

F

(T/F) The IACUC reviews animal protocols before work begins.

T

AAALAC accreditation is mandatory for all institutions

F

(T/F) Humane endpoints help reduce unnecessary suffering

T

(T/F) Personnel training is an important part of animal welfare programs

T

The primary purpose of facility security in an animal research facility is to:

Protect animals, personnel, & research integrity

Which of the following is considered a security measure?

Controlled access using key card or codes

Unauthorized individuals entering an animal facility may:

Pose risks to animals & research programs

If you observe suspicious activity in an animal facility, you should:

Report it according to the facility policy

Emergency contact information should be:

Easily accessible to personnel

What is the first priority during an emergency?

Ensuring human safety

A disaster plan should include:

Emergency contacts and evacuation procedures

During a fire emergency, personnel should:

Follow facility evacuation procedures

Which emergency could affect animal welfare & facility operations?

All that is mentioned

Backup generators are important because they:

Maintain critical systems during power failures

Animal facility personnel should be familiar with:

Facility emergency response plans