Med Chem II Final

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Last updated 9:48 PM on 4/24/26
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8 Terms

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H1 Antihistamines- amine ethanols/ethers

diphenhydramine

carbinoxamine maleate

clemastine fumarate

doxylamine

2
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H1 antihistamines- Ethylendiamines

pyrilamine

thonzylamine

3
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H1 Antihistamines- Cyclizines

Chlorcyclizine

Meclizine

4
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H1 receptor function and location

Gq; Increase IP3 and DAG

smooth muscle, brain

5
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H2 receptor function and location

Gs; increase cAMP

gastric mucosa; cardiac muscle

6
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H3 receptor function and location

Gi; decrease cAMP

brain, neurons

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H4 receptor function and location

Gi; decrease cAMP

neutrophils, mast cells

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Formation of histamine

from AA L-histidine by the enzyme histadine decarboxylase