Blood Physiology Practice Questions

From Aka

In which of these animals do you find Howell-Jolley bodies in at least 1% of their normal erythrocytes?

Cats

The normal process of blood coagulation following vascular damage depends on some factors and events. Which of these is not included in that group?

Release of prostacyclin by the endothelial cells of the damaged blood vessel

A dog was brought to your clinic and after physical examination you suspected that this dog is anemic and you then conducted some hematological examinations. The laboratory result showed the following values: Total red blood cell count, 10 × 10⁶/microliter, packed cell volume (PCV) 45%, and hemoglobin 8 g/dL. Using these values what will be the mean corpuscular volume (MCV) of this dog?

45 femtoliters

In bacterial infections, which of the following is most likely to increase markedly?

Neutrophils

Which of these proteins facilitates the transport of chloride from the plasma into the red blood cells?

Band 3 proteins

Monocytes are largely attracted to tissues by which of these?

Chemokines and lymphokines

A shift to the left in the differential leucocyte count means?

An increase in the number of immature neutrophils (band cells) in circulation

When red blood cells are hemolyzed, hemoglobin is released, transported by ___1___ in plasma (intravascular hemolysis) and when phagocytized and destroyed by mononuclear phagocytic cells (extravascular hemolysis) it is broken into ___2___ and globin. The former is consequently broken down to ___3___ and iron. ___3___ is then converted to ___4___ which is either ___5___ or ___6___ in the liver. Which of the following options provides the correct answers for the spaces provided?

1. haptoglobulin, 2. heme, 3. biliverdin, 4. bilirubin, 5. conjugated, 6. unconjugated

Tissue macrophages are derived from…

Monocytes

Which of the following statements is correct?

Erythropoietin when secreted takes about 5-7 days after secretion to have effect

Which of these would be the classical description of the anemia in a dog whose MCV and MCH are below normal range?

Microcytic hypochromic anemia

As one of the factors necessary for the haemoglobin formation, copper performs which of the following functions?

Required for the absorption of iron

The protein unit of hemoglobin…

is composed of 4 polypeptides of 2 alpha and 2 beta polypeptide units

A 2-year-old comes to your clinic with primary complaint of chronic emaciation, weakness, lack of appetite and occasional vomiting. You examined this dog and found no flea infestation. You took fecal samples for worm egg count which showed fecal eggs characteristic of stomach worms. Gastroscopy confirmed presence of stomach worm Physaloptera spp. You suspected gastritis and stomach ulceration due to worm burden. You determined the packed cell volume which is lower than 25%. You concluded that this dog is anemic. Which of these best describes the type of anemia that this dog has?

Pernicous anemia which is macrocytic or megaloblastic

The determination of the percentage distribution of white blood cells is known as ___1___ which can be expressed as ___2___ in percentage or ___3___ expressed as per microliter for each leukocyte type. To prevent misinterpretation of the result of the distribution of white blood cells count, ___4___ is best relied on.

1. differential white blood cell count, 2. Relative number, 3. Absolute number, 4. Absolute numbers of each white blood cell