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Failure to Thrive
Syndrome of: weight loss, decreased appetite, poor nutrition, inactivity
Often accompanied by: dehydration, depressive symptoms, impaired immune function, low cholesterol
FTT Incidence
Community: 5-35%
Nursing Home: 25-40%
Hospitalized Veterans: 50-60%
no
is FTT a diagnosis?
FTT - Associated
Increased infection rates
Decreased cell-mediated immunity
Hip fractures
Decubitus ulcers
Increased surgical mortality rates
Causes - FTT
Multifactorial
Chronic concurrent diseases
Functional impairments
Can be hard to ID or irreversible
FTT manifestations
Weight loss
Decreased appetite
Poor nutrition
Inactivity
23%
__________ of older community-dwelling people have problems with 1 or more ADLs
28%
________ of older community-dwelling people have problems with 1 or more IADLs
Up and Go Test
Patient rises from sitting, walks 10 feet, turns and returns to chair to sit
-<10 seconds: Normal
->11 seconds: at risk for falls
->20 seconds: serious fall risk
Malnutrition
When sufficient energy and/or protein is not available to meet metabolic demands
Predisposes patient to poor clinical outcomes
-increased rate of mortality
-prolonged hospitalization
-slower clinical improvement
Malnutrition Consequences
Associated with FTT
Weight loss > 5% loss in 1 month or 10% in 6 months
Normal aging: 0.1-0.2 kg loss per year after 70 yrs
1st Degree Malnutrition
85-95% of expected weight
2nd Degree Malnutrition
75-85% of expected weight
3rd Degree Malnutrition
<75% of expected weight
mortality
malnutrition is an independent predictor of what?
Malnutrition Eval Indications
Unintentional weight loss
Suspected protein or caloric malnutrition
Hospitalized patients with risk factors
-No eating within 5 days
-Nutrient losses
-Serum albumin <3.2 g/dL
-Chronic debilitating condition -> alcoholism, cancer, diabetes, renal dz, advanced age
Malnutrition Assessment
Eval Diet: caloric intake, availability of food, supplements, balance of nutrients
Trend body weight
Assess for muscle wasting
Assess for oral pathology -> dentures, poor dentition, difficulty swallowing
Food Insecurity
Cognitive Impairment
MMSE
Eval mood, social setting -> depression, delirium, look at causes (meds, social setting, elder abuse, recent loss, financial resources)
Frequent assessment is key as mental status can change quickly
≤24
MMSE score of ________ means increased odds of dementia, abnormal, mild cognitive impairment
25-26
MMSE score of ________ means decreased odds of dementia
>=27
MMSE score of _________ means no cognitive impairment
Depression
Can be a cause and consequence of FTT
Screen all FTT patients
Physical complaints more common than traditional symptoms
Delay in diagnosis and treatment -> accelerated decline
FTT Comorbidities
Infections (UTI, pneumonia)
Psych (Depression)
Neuro (Dementia, Delirium, Stroke, Parkinson)
Endocrine (Thyroid Dz, Diabetes)
MSK (Arthritis, muscle wasting)
ENT/oral (cerumen impaction, poor dentition)
Chronic Dz (COPD, CHF, CA)
FTT - HX
patient and caregiver (multidisciplinary team)
Social, environmental, meals, oral health
PX - FTT
Oral exam
ENT
Vitals (orthostatic)
Neuro
Abdominal/Rectal
MSK
Metabolic Eval - FTT
look for evidence of electrolyte imbalance, nutritional deficits, infections, hormonal problems, malignancy, etc
Imaging - FTT
CXR, other investigation for malignancy
Lab Eval - FTT
CBC (infxn, anemia)
Metabolic Panel (renal function, electrolytes)
TSH (thyroid disease)
Vit D (if low, associated with falls/decreased functional ability)
Albumin, protein, cholesterol (malnutrition markers)
UA (UTI)
decrease
what happens to cholesterol and albumin during malnutrition?
Malnutrition - Metabolic Function
Decreased Insulin
GH resistance --> GH high or normal
Increased cortisol
Decreased hepatic function
Decreased mineral stores
Malnutrition - Serum Prealbumin
<15 mg/dL
Powerful predictor of overall illness and severity
Separate test from CMP
<3.4 mg/dL
what is the value of serum albumin in geriatric malnutrition?
<200 mg/dL
what is the value of serum transferrin in geriatric malnutrition?
<1500/mm^3
what is the value of total lymphocyte count in geriatric malnutrition?
<160 mg/dL
what is the value of total cholesterol in geriatric malnutrition?
Meds that Impair Taste/Smell
Allopurinol, Alcohol, ACEi
Beta lactams, BB
CCB (except diltiazem), Chemo agents
HCTZ
Levodopa, Losartan, Lovastatin
Metronidazole
Nicotine patches, Nitroglycerin, NSAIDs
Opiates
Spironolactone
Terbinafine, Tetracycline
Conditions that Impair Taste/Smell
Illness (Covid, sinus infxn, oral infxn, allergies)
Head injury
Hormone Changes
Burns
Hx of radiation, chemical exposure, or cocaine use
Underlying Cause Tx - FTT
Infections
Chronic medical conditions - optimize tx
Depression --> SSRIs, SNRIs, Consider psych consult
paroxetine and citalopram
what SSRIs should be avoided in depression in geriatrics?
Malnutrition Treatment Plan
Diet Supplementation - Boost, Ensure, Multivitamins
Appetite Stimulants -> Mirtazapine, Marinol
Mirtazapine
helps sleep, appetite, depression
study amongst Alzheimer patients treated with this for 3 months showed they each gained 2kg on average
Megace 800 mg BID
potentially inappropriate medication to be avoided in patients 65 years and older due to an INCREASE risk of thrombotic events and potentially DEATH in older adults, with minimal SE on weight
Improving Nutrition
Soft and Colorful foods
Serve small and frequent meals
Make mealtime enjoyable -> social activity, games, tv shows
Have snacks available for easy access
Take advantage of nutritional services
Multidisciplinary Referral - Malnutrition
Dietician
Social Worker
PT and OT; consider exercise
Psychiatrist
Podiatry
Dentist
Ophthalmologist
no!
is disease a normal consequence of aging?
≥ 64 oz
how much water is needed in a day for a geriatric patient?
21-30g/day OR 14g/1000kcal
how much fiber is needed in a day for a geriatric patient?
1600-200 kcal/day for women; 2000-2600 kcal/day for men
how many calories are needed in a day for a geriatric patient?
45-56g/day
how much protein is needed in a day for a geriatric patient?
130 g/day
how many carbs are needed in a day for a geriatric patient?
<=30% of daily calorie intake
how much fat is needed in a day for a geriatric patient?