M4 group act

Acetylcholine

This neurotransmitter release preganglionic sympathetic neurons?

Pre synapse and post synapse

Receptors are present in which part of the synapse?

Enteric Nervous System (ENS)

Third division of the Autonomic Nervous System (ANS)?

Tyrosine hydroxylase

When this enzyme is inhibited by DA & ?

Vesamicol

It block the storage of Ach?

Cholinesterase inhibitor

Agents specifically reactivate acetylcholinesterase or use in organophosphate poisoning?

Guanethidine

Give one agent that inhibit exocytosis of NE?

Homovanillic acid (HVA)

Product of metabolism of dopamine?

Vanillylmandelic acid (VMA)

Product of metabolism of NE?

Alpha 1 / Beta 1

Synaptic increase blood pressure specifically activation of which adrenergic receptor?

Alpha 2

Agonism of which sympathetic receptor helpful mechanism glucagon management?

SYMPATHETIC

• Brochodilation

• Epineprine release

PARASYMPATHETIC

• Eccrine sweating

• Urine incontinence

Epinephrine

First line agent for anaphylactic shock?

Dobutamine

First line agent for cardiogenic shock?

Benign Prostatic Hyperplasia - BPH

Tamsulosin used for?

Phenylephrine hydrochloride (HCL)

Specific a1 agonist for mydriatic in eye examination?

Methyldopa

This antihypertensive cause false positive for hemolytic anemia?

Dobutamine

Synthetic catecholamine and beta-1 adrenergic agonist used in pharmacologic stress testing (like stress echocardiography) for patients unable to exercise.

Methacholine

Agents use for pulmonary test?

Tocolytic/Pre term labor

Isoxsuprine use for what?

Terbutaline

A long acting b2 agonist primarily administered subcutaneously?

Mirabegron

Beta 3 selective agonist?

Hydroxyamphetamine (Horner’s Syndrome)

Enhance of NE exocytosis?

Modafnil

First line agent for narcolepsy?

Cocaine

The only local anesthetic that also acts as a vasoconstrictor?

Nebivolol

Stable chronic heart failure?

Idazoxan

Alpha 2 blocker with depressant activity

NONE

Only class 4 anti-arrhythmic beta blocker?

Nebivolol

The most cardio selective blocker?

NONE

Activation of which muscarinic that leads to tachycardia (Bradycardia)

Ecothiophate

The only organophosphate currently in active, mainstream clinical use?

COPD and Asthma

Tiotropium use treatment the management of?

Oxybutynin

Medication specifically prescribed to treat overactive bladder (OAB) and urinary incontinence?

NONE

Anticholinergic use for Alzheimers?

Depolarizing

Skeletal muscle relaxant?

NONE

Demenzepine management of?

Suggamadex

Selective relaxant binding agent?