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sensory (afferent) division
carries sensory information from receptors to CNS
motor (efferent) division
carries motor commands from CNS to effector organs
somatic nervous system
controls voluntary movements (skeletal muscle)
autonomic nervous system
controls involuntary movements
sensory neurons
brings sensations into CNS
afferent fibers
sensory axon
interneurons
relay signals from sensory to motor neurons; responsible for higher functions
motor neurons
transport signal to effector
efferent fibers
motor axons
sensory receptors
specialized cells/cell processes that alert CNS about conditions in/out of your body
interoceptors
monitor internal organs/systems; detect dissension, deep pressure, pain
proprioceptors
monitor position/movement of skeletal muscles/joints
exteroceptors
monitor external environment; special senses
ganglion
collection of neuron cell bodies in PNS
somatic sensory neurons
external monitor and body position (propioceptors & exteroreceptors)
visceral (autonomic) sensory neurons
internal monitor (interceptors)
somatic motor neurons
transport signal to skeletal muscles
visceral (autonomic) motor neurons
transport signal to cardiac muscle, smooth muscle, glands, adipose tissue, etc
general senses
senses without a specialized organ
special senses
senses that have receptors located within specialized organs
sensation
signal carried by a sensory pathway; requires receptor activation and sensory neuron activation
perception
conscious awareness of a sensation; requires sensory signal reaches cortex, signal is processes, and signal is sent to be made "aware" of
nociceptors
pain receptors with free nerve endings; do not adapt quickly
thermoreceptors
temperature receptors; free nerve endings in dermis, skeletal muscles, liver, hypothalamus
chemoreceptors
respond to chemical concentrations; substances dissolved in body fluids
mechanoreceptors
respond to mechanical distortion of their plasma membranes
propioceptors
position of joints/muscles
baroreceptors
detects pressure changes
tactile receptors
touch (shape/texture), pressure, and vibration
receptive field
area monitored by single receptor cell
large receptor field =
decreased detail
small receptor field =
increased detail
tonic receptors
slow-adapting, always active; AP frequency reflects level of stimulation; increased stimulus = increases AP frequency
phasic receptors
fast-adapting; normally inactive; become active for a short time when a change occurs in what they are monitoring
adaption
reduction in sensitivity with constant stimulus
peripheral adaptation
receptor threshold increases; activity declines
central adaptation
nuclei along a sensory pathway are inhibited; signal lessened
somatotopy
functional map of the body in the brain
homunculus
somatotope showing the relative size of somatosensory or motor cortex devoted to any specific body area
3-neuron pathway
neuron 1: receptor -> spinal cord/brainstem
neuron 2: spinal cord/brainstem -> thalamus
neuron 3: thalamus -> cerebral cortex
lateralization of 3 neuron pathway spinal nerves
right side receptor -> left cortex
left side receptor -> right cortex
lateralization of 3 neuron pathway cranial nerves
right side receptor -> right cortex
left side receptor -> left cortex
2-neuron pathway
neuron 1: receptor -> spinal cord
neuron 2: spinal cord -> cerebellum
lateralization of 2-neuron pathway
both sides go to both sides:
right -> L&R cerebellar hemispheres
left -> R&L cerebellar hemispheres
upper motor neuron
motor cortex -> midbrain/spinal cord
somatic motor pathways
motor responses (effects) must be sent to a skeletal muscle (effector)
lower motor neuron
midbrain/spinal cord -> effector
somatic motor control process
frontal lobe, premotor cortex, basal nuclei/cerebellum, precentral gyrus, effectors
referred pain
sensation of pain in a a part of the body other than its actual source; strong visceral pain sensations arriving at a spinal cord segment can stimulate interneurons in spinothalamic pathway
parkinson's disease
substantia nigra neurons degenerate, basal ganglia control is spotty; movements become shaky
rabies
virus carried by axons back into CNS through retrograde flow; affects various mental processes, notable invasion of salivary glands
amyotrophic lateral sclerosis (ALS)
progressive degenerative disorder affecting motor neurons in spinal cord, brainstem, cerebrum; destroys upper/lower motor neurons, associated skeletal muscles atrophy; sporadic and inherited
alzheimer's disease (AD)
Progressive disorder causing loss of higher-order cerebral functions; intracellular and extracellular abnormalities in hippocampus (affects memory processing)
multiple sclerosis (MS)
CNS disease characterized by autoimmune-driven demyelination of axons of optic nerve, brain, spinal cord; Common signs/symptoms include impairment of vision, speech, balance, general motor coordination