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Hormonal contraception
Uses synthetic hormones to suppress ovulation and thicken cervical mucus.
Combined pill
Contains oestrogen + progesterone; prevents ovulation.
Progesterone‑only pill
Thickens cervical mucus; sometimes suppresses ovulation.
Implant
Long‑acting progesterone rod; prevents ovulation for 3 years.
Hormonal IUD
Releases progesterone; thickens mucus; reduces bleeding.
Copper IUD
Non‑hormonal; copper is toxic to sperm; prevents fertilisation.
Condoms
Barrier method; prevents sperm entry; protects against STIs.
Diaphragm
Barrier placed over cervix; used with spermicide.
Vasectomy
Permanent male sterilisation; cuts vas deferens.
Tubal ligation
Permanent female sterilisation; blocks fallopian tubes.
LARC
Long‑acting reversible contraception (IUDs, implant).
Dual protection
Using condoms + another method to prevent pregnancy + STIs.
Bacterial STIs
Chlamydia, gonorrhoea, syphilis; treatable with antibiotics.
Viral STIs
HIV, HPV, herpes, hepatitis B; not curable but manageable.
Parasitic STIs
Trichomoniasis, pubic lice.
Chlamydia
Often asymptomatic; causes discharge + pain; treated with antibiotics.
Gonorrhoea
Discharge + pelvic pain; antibiotic treatment.
Syphilis
Painless sore → rash → systemic disease.
HPV
Causes genital warts + cervical cancer; prevented by vaccine.
Herpes
Painful blisters; lifelong virus.
HIV
Attacks immune system; managed with antiretrovirals.
STI prevention
Condoms, vaccination, regular testing.
Menopause
12 months without a period; end of fertility.
Oestrogen drop
Main hormonal change causing symptoms.
FSH rise
Loss of negative feedback increases FSH.
Hot flushes
Caused by thermoregulation changes.
HRT
Hormone replacement therapy to reduce symptoms.
Progesterone in HRT
Required if uterus present to prevent endometrial cancer.
Vaccine mechanism
Introduces antigen → immune memory.
mRNA vaccine
Delivers mRNA instructions to make antigen.
Live attenuated vaccine
Weakened pathogen triggers strong immunity.
Inactivated vaccine
Killed pathogen; safe for immunocompromised.
Subunit vaccine
Contains only antigen fragments.
Toxoid vaccine
Inactivated toxins (e.g., tetanus).
Herd immunity
High vaccination reduces spread.
Screening test
Identifies risk; not diagnostic.
Diagnostic test
Confirms condition; often invasive.
NIPT
Non‑invasive prenatal test using maternal blood.
Amniocentesis
Diagnostic; samples amniotic fluid.
CVS
Chorionic villus sampling; early diagnostic test.
Carrier screening
Identifies recessive gene carriers.
Ethical issues
Autonomy, consent, psychological impact.
Autonomy
Respecting patient choice.
Beneficence
Acting for patient benefit.
Non‑maleficence
Avoiding harm.
Justice
Fair access to care.
Informed consent
Patient must understand risks + benefits.
Ethical dilemma
Conflict between principles.
Thalidomide
1950s drug causing birth defects.
Phocomelia
Limb shortening caused by thalidomide.
Anti‑angiogenic effect
Prevents blood vessel formation in embryo.
Regulatory impact
Led to strict drug safety laws.
Teratogen
Substance causing birth defects.
Alcohol in pregnancy
No safe amount; crosses placenta.
Smoking in pregnancy
Causes low birth weight + SIDS risk.
Opioids in pregnancy
Can cause neonatal abstinence syndrome.
Cocaine in pregnancy
Risk of placental abruption.
Marijuana in pregnancy
Associated with low birth weight.
FASD
Condition caused by prenatal alcohol exposure.
Facial features
Smooth philtrum, thin upper lip.
CNS effects
Memory, attention, learning issues.
Growth restriction
Low birth weight + slow development.
Cause
Alcohol crosses placenta and affects brain development.