Congenital Thrombotic Disorders

Define thrombosis and thrombophilia

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List common causes of thrombotic issues

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Compare and contrast arterial and venous thrombi

List common hereditary and acquired causes of venous thromboembolism

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Recall control systems of the hemostatic process

Explain how inhibition of hemostatic control systems can increase the risk of thrombosis

Describe the etiology, pathogenesis, genetics, and laboratory methods and findings of the following:

Antithrombin deficiency

Protein C and S deficiencies

Factor V Leiden

Prothrombin G20210A Mutation

Hyperhomocysteienemia

Factor XII Deficiency

Plasminogen Deficiency

Explain how higher concentration of coagulation factors can increase thrombotic risk

Select the next best laboratory test when given a case study related to thrombotic conditions

Determine the thrombotic condition when provided appropriate data

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