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What are the functions of the urinary system?
Filtering blood, Excreting Waste
What happens when filtering blood?
Adjusts composition, pH, volume, pressure, osmolarity
What is the structure of the Urinary System?
Kidneys, Ureters, Bladder, Urethra
What is the function of the kidneys?
Filteration
What is the function of the ureters?
Carry urine to the bladder
What is the function of the Bladder?
To store Urine
What is the function of the Urethra?
Carry urine to outside during urination
What is the structure of the kidneys?
Right slightly inferior to left, protected by floating ribs, posterior to the peritoneum
What is the Renal Hilum?
Concave medial border, where renal artery/vein/ureter emerge
What are the 3 layers of the kidney (external)
Renal capsule, Adipose capsule, Renal fascia
What is the renal capsule?
1st layer of kidney, Deepest, Dense irregular CT
What is the Adipose Capsule?
2nd layer of kidney, made of adipose CT
What is the renal fascia?
3rd layer of kidney, Superficial, dense irregular CT
What are the two internal structures of the kidney?
Outer renal cortex & Inner renal medulla
What are Renal pyramids?
Base near cortex, renal papillae near hilum, and separated by renal columns
What do nephrons do?
Drain filtrate into papillary ducts in renal papillae
Where do papillary ducts drain?
Minor Calyces 8-18 per kidney
Where do minor calyces drain?
Major Calyces 2-3 per kidney
Where do major calyces drain?
Renal pelvis, continuous with ureter
What are the 2 functional units of the kidney?
Renal corpuscles & Renal Tubule
What happens in renal corpuscles?
Blood plasma is filtered
What happens in Renal Tubule?
Filtered fluid travels through
What are nephrons associated with?
Blood capillaries, afferent arteriole, glomerulus
What are Efferent Arterioles?
Divides to form peritubular capillaries, vasa recta
What are the parts of the renal corpuscles?
Glomerulus ( capillary network) & Glomerular capsule (epithelial cup surrounding glomerulus)
What are the parts of renal tubule?
Proximal convoluted tubule, nephron loop (descending & ascending), Distal convoluted tubule
What are the 3 processes of nephron function?
Glomerular filteration,Tubular reabsorption, Tubular secretion
What is the function Glomerular filtration?
Water and most solutes in blood plasma are filtered into capsules
What is the function of tubular reabsorption?
Most water and useful solutes are reabsorbed from the renal tubes into the blood
What is the function of tubular secretion?
Renal tubule cells secrete other wastes, drugs, excess ions into tubules
Will be excreted as waste in urine
What is the structure of Glomerular filtration?
Ball-like glomerulus ( fenestrated blood capillaries)
supplied by afferent arteriole
Efferent arteriole
What is a glomerular corpuscle?
Parietal layer
Visceral layer made of podocytes with projections called pedicles
Capsular space in between, where filtered plasma initially collects
What % of blood plasma in glomerular filtration?
16-20%
Where is the blood plasma filtered in glomerular filtration?
Filtered into capsular space
What happens in proximal convoluted tubule (PCT)?
Most reabsorption occurs
During PCT what things are absorbed?
Water, Glucose, amino acids, N+,K+,HCO, Ca+, Mg+,Urea