Replication Enzymes (Genetics)

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Last updated 4:57 AM on 5/27/26
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9 Terms

1
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Helicase

Unwinding of helix (1)

2
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Single stranded binding proteins

Prevents helix from renaturing (2) coat open bubble NOT bonded

3
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Primase

Synthesis of primer for initiation (3)

4
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DNA pol (polymerase) III

Leading strand of synthesis (4) reading template

5
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Processivity factor (Clamp)

Discontinuous synthesis of second/lagging strand (5) grabs the lagging and flips/loops it

6
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DNA pol (polmerase) I

Removal of the RNA primers (6)

7
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Ligase

Joining of the gap-filling DNA to adjacent strand (7)

8
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DNA pol (polymerase) III

Proofreads (8)

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Topoisomerase

Reduce increased coiling generated during unwinding (9) cuts ahead of the advancing fork