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Hormones
chemical messengers produced by endocrine glands that travel through the bloodstream.
Target cells
cells with receptors that respond to specific hormones
Prostaglandin
lipid compounds produced in nearly all body tissue to regulate inflammation, blood flow, uterine contractions, and protect stomach lining.
Tropic hormone
specialized hormones that regulate function/secretion of other glands.
Catecholamines
hormones and neurotransmitters produced by the adrenal glands and nervous system in response to stress
Mineralocorticoids
steroid hormones, primarily aldosterone, that regulate sodium retention and potassium excretion, crucial for maintaining fluid balance and blood pressure
Glucocorticoids
potent, steroids-based anti inflammatory and immunosuppressive agents
Diabetes mellitus
inadequate insulin production (Type 1) or ineffective insulin use (Type 2)
Diabetes insipidus
disorder characterized by extreme thirst (polydipsia) and the excretion of large amounts of dilute urine (polyuria)
What are most hormones regulated by?
Negative feedback.
Three types of stimuli
hormonal, humoral, neural
Example of hormonal stimuli
the hypothalamus releasing TRH, which signals the anterior pituitary to secrete TSH, making the thyroid gland to release thyroid hormone
Example of humoral stimuli
the regulation of blood sugar, calcium, and water balance
Example of neural stimuli
“fight-or-flight” response, increases heart rate and oxygen delivery.
Hypothalamus; where are its hormones stored?
posterior pituitary
ADH and how alcohol affects it
Alcohol suppresses the release of ADH from the pituitary gland. Low ADH means kidneys do not reabsorb water, leading to diuresis and dehydration.
Oxytocin
a hormone and neurotransmitter produced in the hypothalamus that acts as the body's primary driver for labor, lactation, and social bonding.
Posterior pituitary stands out because it is.…
NOT a part of the endocrine system.
Anterior pituitary
controlled by hypothalamus. produces 6 hormones.
Growth hormone
growth, cell regeneration, metabolism. Effects bones and muscles
Prolactin
stimulates milk production in mammary glands
ACTH
stimulates the adrenal cortex to produce cortisol
TSH
Produced by the anterior pituitary gland to stimulate the thyroid gland
FSH
vital for sexual development and reproduction. drives maturation of eggs and regulates sperm production.
LH
Triggers ovulation of an egg in females. Stimulated testosterone production in males.
Thyroid
contains Calcitonin and thyroid hormone (thyroxine)
Calcitonin and thyroid hormone effects
reduces kidney calcium reabsorption and regulates calcium levels. Thyroid hormone controls the body’s metabolism, body temperature, and basic homeostasis.
Parathyroid
produces PTH. Located behind the thyroid.
PTH effect
increases calcium presence in blood when levels are low.
Adrenal cortex
on top of kidneys, responsible for adrenaline rushes. Produces aldosterone and cortisone.
Aldosterone and cortisone effects
fight for flight response, adrenaline rush like increase heart rate and oxygen delivery
Pancreas
produces insulin and glucagon
Insulin and glucagon effects
control blood sugar levels
What cells make hormones in the pancreas?
Islets of Langerhans
Thymus
produces thymosin
Thymosin effect
immune system production (T cells)
Ovaries
produces estrogen and progesterone. In females
Estrogen and progesterone effects
estrogen affects bone health, mood, and egg maturation, while progesterone stabilizes the uterine lining for pregnancy.
Testes
produces testosterone. In males
Testosterone effects
regulates libido, sperm production, muscle mass, and bone density.
Pineal
produces melatonin
Melatonin effects
controls sleep/wake cycle.
Placenta
produces human chorionic gonadotropin (pregnancy hormone)
What is the rule of Iodine
Iodine is needed to synthesize thyroid hormone.
Symptoms of diabetes
Thirst, polyuria, hunger, and fatigue.
(Open ended) PTH and Calcitonin
regulate calcium homeostasis. PTH increases blood calcium when levels are low, calcitonin does the opposite.
(Open ended) What insulin does
vital peptide hormone produced in the pancreas that regulates blood sugar by allowing cells to use glucose as energy.