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Cytokinesis
the final split of the cytoplasm into two daughter cells
Chromosomes
coiled structures of the DNA and proteins
chromatids(sister)
identical copies of a chromosome held together before division
Centromere
Region where sister chromatids are held together
Cancer
a disease caused by the uncontrolled cell growth and division
Cell cycle
The full cycle of a cell, including growth and division
Interphase
the preparation phase(g1, s, g2) where the cell grows and copies its DNA
Mitosis
Nuclear division resulting in two identical cells
Diploid
having two complete sets of chromosomes 2n
Haploid
having a single set of chromosomes n
Homologous chromosomes
chromosome pairs(one from each parent) with the same gene sequence
Crossing over
the swap of genetic material between homologous chromosomes
Independent assortment
the random way chromosome pairs line up, creating genetic variety
Haploid(n)
one set of chromosomes
Diploid(2n)
two sets of chromosomes
S - Phase
apart of interphase where DNA replication occurs
Synapsis
Tight pairing of homologous chromosomes during prophase 1
Chiasmata
X shaped region where crossing over occurs
Independent Assortment
Random distribution of maternal and paternal homologs into gametes
Nondisjunction
Failure of chromosomes or chromatids to separate during anaphase
Apoptosis
programmed cell death, occurs when cell fails checkpoint and cannot repair DNA
Cdk
Enzyme that phosphorylates target proteins to drive the cell cycle and only active when bound to cyclin
Crossing Over
physical exchange of DNA segments between non-sister chromatids to create new “recombinant” alleles