pyrimidine synthesis
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18 Terms
jpyrimidine step 1
carbamoyl phosphate synthetase 2
carbamoyl phsophate synthetase 2
glutamine to carbamoyl phosphate
pyrimidine step 2
transcarbamoylase
transcarbamoylase
carbamoyl phosphate to carbamoyl aspartate
pyrimidine step 3
dihydroorotase
dihydroorotase
carbamoyl aspartate to dihydroorotate
pyrimidine step 4
dihydroorotate dehydrogenase
dihydroorotate dehydrogenase
dihydroorotate to orotate
pyrimidine step 5
orotate phosphoribosyl transferase
orotate phosphoribosyl transferase
orotate and phosphoribosylpyrophosphate to orotidine monophosphate
pyrimidine step 6
orotidylic acid decarboxylase
orotidylic acid decarboxylase
orotidine monophosphate to uridine monophosphate
ctp synthetase
utp to ctp
thymidylate synthase
dump to dtmp
2 possible starters to make dump
udp and dcmp
inhibited by…
ctp
activated by…
phosphoribosylpyrophosphate
rate limiting step
carbamoyl phosphate synthetase 2