Drug Stuff and Interactions

Drug Classes

-floxacin * Quinolone Antibiotics

-azole * Antifungal

-olol * Beta Blocker

-vir * Anti-Viral, Anti HIV

-zosin * Alpha Blockers

-statin * Cholesterol Lowering

-pril * ACE Inhibitor

Adverse Gastrointestinal Effects Examples

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Aspirin, KCl

Esophageal Ulcer

NSAIDS/theophylline

Esophageal Reflux

NSAIDS

Gastritis

Iron and Calcium Supplements

Constipation

Antibiotics (Hint C Diff. and taking dumps)

Diarrhea

Drug-Drug Interactions Examples

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Antacid decreases the effects of…

Cimetidine, ketoconazole, and tetracycline

Iron tablets decrease the effects of…

Levothyroxine

Aspirin, Acetaminophen (tylenol), NSAIDs, Bactrim, and amiodarone increases the effects of…

Warfarin

Vitamin K decreases the effects of…

Warfarin

Antibiotics decrease the effects of…

Oral Contraceptives

Drug-Disease Correlations Examples

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Antacids cause…

Kidney disease

NSAID’s (Aspirin, ibuprofen, and naproxen) can cause…

kidney disease

Antitussives can cause…

Glaucoma

Beta Blockers (atenolol) can cause…

asthma

Nasal Decongestants (sudafed) can cause…

heart disease

Nicotine Substitutes can cause…

asthma and depression

Nighttime Sleep Aids (melatonin) can cause…

memory problems

Drug-Dietary Supplement Examples

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Black Cohosh can increase…

estrogen activity

Ginkgo Biloba may increase risk of bleeding when paired with…

NSAIDS, Clopidogrel, and Warfarin

St. John’s Wort can increase risk of liver damage when paired with…

Acetaminophen

St. John’s Wort may decrease the effectiveness of…

Warfarin

St. John’s Wort can decrease levels of…

cyclosporine

St. John’s Wort can decrease levels of…

Estrogens

St. John’s Wort may decrease blood concentration when paired with…

HIV Antiviral Drugs along with effectiveness of HIV

St. John’s Wort may increase the pharmacological effects and risks of toxicity of…

Paroxetine

St. John’s Wort may increase toxicity risk when paired with

Venlafaxine

Drug-Nutrient Examples

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Grapefruit Juice increases the effects of…

Alprazolam, Amiodarone, Atorvastatin (cholesterol lowering), amlodipine (Ca channel blockers), and carbamazepine

Caffeine can increase the effects of…

methylphenidate (central nervous system stimulants)

Vitamin K can decrease effects of…

Warfarin

Drug/drug classification/food-laboratory test examples

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Blood glucose tests elevate blood sugar when paired with…

Barbiturate, thiazide, diuretics, aspirin, corticosteroids, and sudafed

Blood glucose tests decrease blood sugar when paired with…

Beta blockers, aspirin (children), trimethoprim, and sulfamethoxazole

Prothrombin Time / International Normalized Ratio tests can be decreased when paired with…

Warfarin

In cholesterol lab tests, cholesterol levels are elevated by…

thiazide diuretics, estrogens, and prednisone

In cholesterol lab tests, cholesterol levels are decreased by…

Beta blockers

Dietary Supplements : Vitamins - Fat Soluble Examples

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Vitamin A / Retinol

Prevents eye disorder

Vitamin D2 / Ergocalciferol

Prevents rickets in small children.

Vitamin D3 / Cholecalciferol

Prevents bone loss

Vitamin E / Tocopherols

are an antioxidant

Vitamin K / Phytonadione

Helps with formation of prothrombin (blood thickener)

Dietary Supplements : Vitamins - Water Soluble Examples

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Vitamin B1 / Thiamine

Helps body change carbs into energy

Vitamin B2 / Riboflavin

Helps with cellular function

Vitamin B6 / Pyridoxine

Maintains health of nerves, skin, and red blood cells

Vitamin B9 / Folic Acid

Helps with red blood cell formation and prevents birth neural tube effects

Vitamin B12 / Cyanocobalamin

helps with red blood cell formation

Vitamin C / Ascorbic Acid

Is an antioxidant (support immune system)

Useful Electrolytes/Minerals

Ca, Cr, Cu, I, Fe, Mg, K, Na, S, Zn