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paracrines
which group of messengers is defined as acting on cells within the same tissue
The blood
A major difference between neurotransmitters and hormones is that hormones reached their destination via (….)
Whether the hormonal molecule is hydrophobic or hydrophilic
A major determinant of a hormones mechanism of action is?
Inside the target cell
Receptors for steroid hormones are commonly located
A receptor
In order for a hormone to activate a target cell, the target cell must possess
Effective is coordinating cell, tissue, and organ activities on a sustained, long-term basis
Which of these characteristics is exclusive to the endocrine system then compared with the nervous system?
A second messenger
Interaction with a membrane bound receptor will transduce the hormone message via
Small concentrations of hormone can reactivate many intracellular signals via amplification
Second messenger, activating hormones, circulate in minute quantities because?
cAMP, Ca2+, inositol triphosphate
Which of the following molecules act as second messengers
Humoral
When the pancreas releases insulin indirect response to blood glucose, this is example of (…..) stimulation
Neural
When an infant circles at his mother’s breasts, the mother’s neurophysis releases oxytocin this is an example of (…..) stimulation
Hormonal
When the ovaries secrete estrogen and response to the hormone, GNRH, this is an example of what stimulation
Negative feedback
Blood levels of hormones are kept within a very narrow range by (…) mechanisms
ADH
Which hormone is produced in the hypothalamus
Anterior pituitary
Hormone secreted into the hypophyseal portal system are detected by the …
Insulin like growth factors
The long bone growth promoting affects of growth hormone are mediated by ….
Adrenal cortex; gonads
Secretion from the corticotrophs activate cells of the ……., While secretions from the gonadotrophs affect cells of the ……
Hyper secretion of ADH
A patient is displaying high volumes of urine output and severe hydration. This is most likely cause by …..
lumen of follicle
Where is iodine located in the thyroid gland?
Increasing calcium absorption in the intestines
Which of the following is an indirect effect of PTH?
Hyperthyroidism
A patient is losing weight rapidly, sweating profusely, and is always anxious. The patient may be suffering from.
Glucocorticoids and gonadocorticoids
Occasionally, a female patient will experience hirsutism, however, blood test revealed that her levels of testosterone are normal for a female. Another cause could be hyper secretion of?
Aldosterone
(…) is the adrenal hormone responsible from maintaining appropriate blood sodium levels
Less water is reclaimed by osmosis in the kidneys
Water loss reduces blood volume, promoting secretion of ADH
Why are diabetics continuously, thirsty and why do they frequently urinate?
Both increase blood glucose levels and promote the breakdown of stored fats into fatty acid
What ways are hormonal effects of ENNE from the adrenal medulla similar to the effects of glucocorticoids from the Zona fasciculata
Transport of glucose into most body cells
Which of the following is not an action of glucagon?
Melatonin
The secretion of (blank) helps regulate our circadian rhythms
Kidney
Which of the following structures produces a hormone responsible for stimulating red blood production
Skin
Which of the following structures produces a precursor to hormonal, vitamin D, important for Ca2+ regulation
Buffy coat
After centrifuging, which of the listed blood components, contains the components of immune function
Maintenance of plasma osmotic pressure, buffering changes in plasma pH
The major function of the most common plasma, protein, albumin, is?
Red blood cells are biconclave discs
Red blood cells are you efficient, oxygen transport cells period of the following characteristics, which is the major contributor to the significant oxygen carrying capacity of a red blood cell
4
Each hemoglobin can transport (blank) oxygen
Iron atom
Oxygen binds to the (blank) portion of hemoglobin
And increase in fatigue
A patient with low iron levels with experience, which of the following symptoms
Erythrocytes, leukocytes, platelets
a hematopoietic stem cell will give rise to
The blood viscosity increases to levels that may induce heart attacks or strokes
Predict the outcome of an overdose of the hormone erythropoietin
The kidneys would secrete elevated amounts of erythropoietin
What response would you expect after traveling to high altitude for two weeks
Would have a decreased number of red blood cells
If a patient has pernacious anemia, the ability of the body to absorb vitamin B12 the patient…..
acute bacterial infection
An elevated neutrophil count would be indicative of
basophils
Antihistamines counter, the actions of which white blood cell
Over reproduction of abnormal leukocytes
Leukemia is a general descriptor for which of the following disorders
Megakaryocyte
A (blank) is the progenitor of platelets
only contacted platelets with exposed collagen, fibers, and Von Willie brand factor causes them to be sticky and form plugs
Why don’t platelets form plugs in undamaged cells?
Tissue factor III
Activation of the astringent pathway of coagulation requires exposure of the blood to …..
Rapid blood flow washes away and dilute activated clotting factors, thrombin is an activated by antithrombin III if it enters the general circulation
Why doesn’t a clot fill the entire vasculature system once it has started forming
Is a risk of embolism
An injectable heparin medication might be prescribed for a patient who
Anti-A
Which agglutinins are naturally presented in someone who is B positive?
Pericardium
What is a double wall sack covering the heart termed
Myocardium
Of the following layers of the heart which consumes the most energy
Pulmonary artery, pulmonary veins
Which of the following structures is an exception to the general principal surrounding blood vessel, oxygenation levels
Equal volume of blood are pumped into the pulmonary and systemic circuits at any moment
Which of the following statements is true?
Right ventricle and flows directly into the lungs
During pulmonary circulation, blood leaves the…..
Left ventricle and flows directly to the aorta
During systemic circulation, blood leaves the…..
Right atrium, right ventricle, lungs, left atrium, left ventricle
From the perspective of blood, returning for the systemic circuit, identify the correct sequence of blood flow through the chambers of the heart
right atrium and right ventricle
The tricuspid valve is located between the….
The Mitral valve
Which of the following vowels is the most often faulty in the heart?
Functional syncytium
The presence of integrated discs between adjacent cardiac muscle cells causes the heart to behave as
The cells are each innervated by a nerve ending
Cardiac muscle cells have several similarities with skeletal muscle cells. Which of the following is not a similarity.
An influx of calcium ions
The plateau portion of the action potential and contractile cardiac muscle cells is due to
A pacemaker potential
The stimulus of the hearts rhythmic contractions comes from
Sinoatrial node
In a normal hard, which of the following structures is responsible for setting the hearts pace
The rhythm would be slower
Predict the nature of an ECG recording, when the atrial ventricular node becomes the pacemaker
Junctional rhythm
Which heart abnormality has no P waves on an otherwise normal ECG
Left ventricle; left atrium; mitral valve
A heart murmur will be detected when blood is heard flowing from the BLANK to the BLANK through the BLANK
The closing of the atrioventricular valves “lub” and the closing of the semi lunar valves “dup”
The lub dup heart sounds are produced by
After
Atrial systole occurs BLANK the firing of the sinoatrial node
Passively through blood flow alone
The majority 80% of ventricular feeling occurs
Heart rate and stroke volume
Cardiac output is determined by
It would decrease
Predict what would happen to the end systolic volume if contraction force were to increase
Due to norepinephrine causing threshold to be reached more quickly
Your heart seems to pound after you’re hear a sudden loud noise this increased contractility is
Tunica media
Of the following blood vessel components, which is the most critical regulating systemic blood pressure
Vasodilation, relaxes
In increasing women diameter is termed BLANK and occurs when smooth muscle BLANK
Veins
Of the following vessel types, which conduct blood towards the heart
Capillaries
Of the following vessel types, which are responsible for the exchange of gases in nutrients with tissues
Systemic veins and venules
Of the following cardiovascular components, which contains the majority of the blood volume at one time
Brain; bone marrow
Some of the least permeable capillaries are found in the BLANK, while some of the most permeable capillaries are found in the BLANK
peripheral resistance decrease
Predict the change in peripheral resistance as blood vessel diameter increases
The muscular arterioles do not exhibit elastic rebound
Pulse pressure disappears by the time blood reaches capillary beds because….
It causes blood pooling and slowing a blood flow
What effect is prolonged standing in one position have on blood flow?
Venous returned to the heart
What is the major factor controlling stroke volume during resting periods?
Vasodilation in vessel, supplying, skeletal muscle
Predict what might happen to peripheral resistance in aterioles supplying skeletal muscle when pH levels drop
Stretch in atrial walls
Baroreceptors detect changes in
arteriosclerosis
In which disease do the walls of the arteries become thicker and stiffer
Hydrostatic pressure within the capillaries
The primary mechanism driving filtration and capillary beds is….
Nondiffusable plasma proteins; draw fluids into the capillary
Capillary collide, osmotic pressure created by BLANK tends to BLANk
Anaphylaxis
Which of the following would cause vascular shock
mini valves in their walls
Lymphatic capillaries owe their permeability to the presence of
The milking action of skeletal muscle contraction.
Pressure changes in the thorax that result from breathing
Which of the following contributes to the flow of lymph through lymphatic vessels
Bacteria, large proteins, and interstitial fluid
BLANK can enter lymph capillaries
Spleen
The blank is the largest lymphoid organ
T lymphocyte maturation
The thymus is important for
skin and mucous membranes
Which of the following act of the first line of defense against foreign pathogens
Interferon
Which of the following is non-a mechanical barrier to pathogen invasion
Monocytes
Macrophages are derived from
Bacterial cell membrane lysis
The basic mechanism employed by complement to fight bacterial infection is
opsonization
The process of attaching proteins to the bacterial cell wall to enhance phagocytosis is called
An increase in the body temperature set point
Why would the bodies response if the hypothalamus detected pyrogens
MHC
The presence of BLANK proteins makes it possible for immune system to differentiate between ourselves, and those that are foreign
Cell mediate; humoral
The adaptive immune system involves three major cell types: antigen, presenting cells, T cells, which constitute BLANK immunity, and B cells, which govern BLANK immunity