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hemodynamics
the movement of blood
blood circulation
how are body tissues replenished with oxygen and nutrients?
Cardiac Output
volume of blood ejected each minute during ventricular contractions
4-8 L/min
normal cardiac output
Cardiac Index (CI)
the cardiac output corrected for differences in body size (CO/BSA)
2.5-4 L/min
normal cardiac index
Stroke Volume (SV)
Volume of blood ejected during each ventricular systole
60-130ml
normal stroke volume
Ejection Fraction (EF)
percentage of blood pumped out of the left ventricle during systole
Systemic Vascular Resistance (SVR)
the resistance in the systemic vasculature
50-75%
normal ejection fraction
800-1400 dynes/sec/cm5
normal SVR (left heart)
-preload
-contractility
-afterload
name the 3 components of the stroke volume
4-12 mmHg
normal PAWP (Left heart)
0-6 mmHg
normal CVP (right heart)
Starling's Law
states that the more the myocardium stretches during diastole, the more forceful the contraction in systole
-Lasix (diuretic)
-Nitroglycerine (Vasodilator)
name two agents that will REDUCE preload
-Crystalloids
-Colloids
name the two GENERAL TYPES of preload INCREASERS
crystalloids
these are thin preload increasers
colloids
these are thick preload increasers
crystalloid preload increasers
normal saline and lactate ringers are examples of...
colloid preload increasers
blood, plasma, albumin, Hespan, and Dextran are all examples of...
preload
which component of the stroke volume is most affected by atrial kick?
TRUE: The greater the preload, the greater the force of contraction
True or False: Contractility is influenced by preload
decrease contractility
how will hypocalcemia and hypokalemia affect contractility?
Inotropes
agents that increase contractility are called...
-Norepinephrine
-Epinephrine
-Dobutamine
-Dopamine
-Isoproterenol
(N.E.D.D.I)
name 4 inotropes
decrease contractility
how would hypoxemia affect contractility?
decrease contractility
how would cardiac tamponade affect contractility?
20-120 dynes/sec/cm5
normal PVR (right heart)
vessel status
what factor is afterload most dependent on?
Vasodilators
what TYPE of agents REDUCE afterload?
-nitroprusside
-nitroglycerine
name two vasodilators that reduce afterload
afterload
the amount of resistance in the vessels the heart must push against; resistance to ejection
Vasonconstrictors
what TYPE of agent will INCREASE afterload?
-Norepinephrine
-Epinephrine
-Phenylephrine
-Dopamine
name 4 vasoconstrictors that will increase afterload
Inotrope
what kind of drug is digoxin?
Crystalloid
to increase preload, would we first use a crystalloid or a colloid?