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Metabolism
All chemical reactions and physical workings occurring within a cell.
Anabolism
Energy-requiring process that builds complex molecules from simpler molecules; biosynthesis.
Catabolism
Process that breaks down complex molecules into simpler molecules and releases energy.
Enzyme
Biological catalyst that speeds up chemical reactions without being consumed.
Catalyst
Substance that increases the rate of a chemical reaction without being permanently changed.
Characteristics of Enzymes
Protein nature, substrate specificity, extreme efficiency, environmental sensitivity, reversibility, regulation, inhibition, and activation.
Active Site
Specific region on an enzyme where the substrate binds and the reaction occurs.
Substrate
Reactant molecule upon which an enzyme acts.
Factors Affecting Enzyme Function
Temperature, pH, substrate concentration, enzyme concentration, inhibitors, activators, and denaturation.
Denaturation
Loss of an enzyme's three-dimensional shape and function due to environmental changes such as heat or pH.
Exoenzyme
Enzyme produced inside a cell and secreted outside to perform its function.
Endoenzyme
Enzyme that functions within the cell that produced it.
Constitutive Enzyme
Enzyme produced continuously regardless of environmental conditions.
Regulated Enzyme
Enzyme whose production or activity is controlled according to cellular needs.
Exergonic Reaction
Chemical reaction that releases energy.
Endergonic Reaction
Chemical reaction that requires an input of energy.
Relationship of Exergonic Reactions to Metabolism
Typically associated with catabolic pathways that release energy.
Relationship of Endergonic Reactions to Metabolism
Typically associated with anabolic pathways that require energy.
Aerobic Respiration
Process of producing ATP from glucose using oxygen as the final electron acceptor.
Major Stages of Aerobic Respiration
Glycolysis, Pyruvate Oxidation, Krebs Cycle, Electron Transport Chain (ETC), and Oxidative Phosphorylation.
Glycolysis Beginning Product
Glucose.
Glycolysis Ending Products
2 Pyruvate, 2 ATP (net), and 2 NADH.
ATP Yield of Glycolysis
2 ATP (net).
Pyruvate Oxidation Beginning Product
2 Pyruvate.
Pyruvate Oxidation Ending Products
2 Acetyl-CoA, 2 NADH, and 2 CO₂.
ATP Yield of Pyruvate Oxidation
0 ATP.
Krebs Cycle Beginning Product
2 Acetyl-CoA.
Krebs Cycle Ending Products
4 CO₂, 2 ATP, 6 NADH, and 2 FADH₂.
ATP Yield of Krebs Cycle
2 ATP.
Electron Transport Chain Beginning Products
NADH, FADH₂, oxygen, and electrons.
Electron Transport Chain Ending Products
Water and approximately 25–34 ATP.
ATP Yield of Electron Transport Chain
Approximately 25–34 ATP.
Total ATP Yield of Aerobic Respiration
Approximately 29–38 ATP per glucose molecule.
Aerobic Respiration Requires
Oxygen.
Aerobic Respiration End Products
ATP, carbon dioxide, and water.
Anaerobic Respiration
Respiration that occurs without oxygen and uses an alternative final electron acceptor.
Difference Between Aerobic and Anaerobic Respiration
Aerobic uses oxygen and produces more ATP; anaerobic does not use oxygen and produces less ATP.
Fermentation
An anaerobic process that converts glucose into acids, gases, or alcohols while regenerating NAD⁺.
Purpose of Fermentation
Regenerates NAD⁺ so glycolysis can continue in the absence of oxygen.
Lactic Acid Fermentation
Fermentation that converts pyruvate into lactic acid.
Ethanol Fermentation
Fermentation that converts pyruvate into ethanol and carbon dioxide.
Acetic Acid Fermentation
Fermentation that produces acetic acid (vinegar).
ATP Yield of Fermentation
2 ATP per glucose molecule.
Amphibolism
Metabolic pathways that function in both catabolism and anabolism.
Photosynthesis
Process by which light energy is converted into chemical energy.
Two Main Parts of Photosynthesis
Light-dependent reactions and light-independent reactions (Calvin Cycle).
Light-Dependent Reactions
Use light energy to produce ATP and NADPH.
Calvin Cycle
Uses ATP and NADPH to fix carbon dioxide into sugars.
Final Product of Photosynthesis
Glucose.
Overall Photosynthesis Equation
6CO₂ + 6H₂O + Light → C₆H₁₂O₆ + 6O₂