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Atherosclerosis
MCC of vascular disease
Chronic inflammatory disease of arteries characterized by plaque formation within the arterial wall
Can block blood flow
Create clots/thrombi
Atherosclerosis Modifiable RF
Smoking
Obesity
Sedentary lifestyle
Chronic medical conditions: diabetes, HTN, hyperlipidemia
Atherosclerosis Non-Modifiable RF
Age
Sex
Family history
Atherosclerotic Plaque Formation - Anatomic Sites
Carotid bifurcation
Coronary arteries
Aortic bifurcation
Femoral arteries
Popliteal arteries
Why? Branch points and turbulent flow
Atherosclerotic Plaque Formation Comp
Stroke
Buttock claudication/leg ischemia
MI
PAD Surgery Indications
Lifestyle limiting claudication
Rest pain
Tissue loss
Failed endovascular treatment
PAD - Bypass
A surgical procedure that creates an alternate route for blood flow around a blocked artery
Ankle-to-Brachial index
A non-invasive sensitive and specific tool that measures ankle systolic pressure/brachial systolic pressure
Normal >0.90
<0.40
what is a severe ABI?
Femoral-Popliteal Bypass
Femoral artery → popliteal artery
Indications: Significant blockage in: Superficial femoral artery, Above-knee popliteal artery
Causing: Lifestyle limiting claudication, Rest pain, Tissue loss
Femoral-Distal Bypass
Femoral artery → tibial/pedal artery
Femoral-Distal Bypass Indications
More extensive disease involving:
-Femoral artery
-Popliteal artery
-Tibial arteries
Usually seen in:
-Advanced PAD
-Critical limb ischemia
-Diabetic patients
-Tissue loss
-Non-healing wounds
Above Knee Amputation
Higher energy expenditure with prosthesis
Removal of leg above knee
Above Knee Amputation Indications
Tissue loss extends above calf
Severe infection
Poor blood flow preventing BKA healing
Failed BKA
Above Knee Amputation Disadvantages
More energy required for walking
Harder rehabilitation
Worse prosthetic function
Below Knee Amputation
Most functional major amputation
Removal of lower leg while preserving knee
Below Knee Amputation Indications
Severe infection
Extensive tissue loss
Failed revascularization
Non-salvageable foot
Transmetatarsal Amputation
Forefoot level
Amputation through metatarsal bones
Transmetatarsal Amputation Indications
Multiple non-salvageable toes
Extensive forefoot infection
Forefoot gangrene
Toe Amputation Indications
Gangrenous toe
Osteomyelitis limited to toe
Small areas of non-salvageable tissue
Toe Amputation Advantages
Maximum preservation of function
Fastest recovery
Toe Amputation Limitations
Must have adequate blood flow to heal
Ray Amputation
Removal of toe + metatarsal
Indications:
-Infection extends beyond toe
-Gangrene involves metatarsal region
Surgical Amputation Indications
Non-salvageable tissue
Severe infection
Gangrene
Failed revascularization
Acute Arterial Occlusion S/S
Pain
Pallor
Pulselessness
Poikilothermia
Paresthesia
Paralysis
Sudden limb ischemia threatening limb viability
Acute Arterial Occlusion Tx
Thrombectomy/embolectomy (remove clot using catheter)
Catheter directed thrombolysis (clot dissolving medication delivered directly into clot)
Abdominal Aortic Aneurysm
Repair before rupture whenever possible
Symptomatic aneurysm, rupture, or diameter large enough to carry significant rupture risk
AAA Tx
EVAR (endovascular stent graft placed through femoral arteries)
Open aneurysm repair (replace aneurysmal segment with synthetic graft)
Mesenteric Ischemia S/S
Pain out of proportion to exam
Acute bowel ischemia or severe chronic symptoms from inadequate blood flow
Mesenteric Ischemia Tx
Mesenteric artery stenting
Bypass
Carotid Artery Dz/Occlusion
Stroke prevention
Significant carotid stenosis, especially if associated with TIA or stroke symptoms
Carotid Artery dz/occlusion tx
Carotid endarterectomy (surgical plaque removal)
Carotid artery stenting
Subclavian Steal Syndrome
Arm "steals" blood from posterior circulation
Symptomatic arm ischemia or vertebrobasilar symptoms (dizziness, syncope)
Subclavian Steal Syndrome Tx
Subclavian artery angioplasty/stenting
Carotid-subclavian bypass
Renal Artery Stenosis
Secondary HTN
Selected patients with resistant HTN, recurrent flash pulmonary edema, or progressive renal dysfunction
Renal Artery Stenosis Tx
Renal artery angioplasty with stenting
Splenic Artery Aneurysm
Most common visceral aneurysm
Symptomatic aneurysm, enlarging aneurysm, pregnancy, or high rupture risk
Splenic Artery Aneurysm Tx
Endovascular coil embolization/stent graft
Surgical ligation/resection
Popliteal Artery Aneurysm
Often feared for thrombosis rather than rupture
Symptomatic aneurysm, thromboembolism, limb-threatening ischemia, or aneurysm meeting repair criteria
Popliteal Artery Aneurysm Tx
Bypass with exclusion of aneurysm
Endovascular stent or graft placement