PIP Calcium Mechanism

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Nursing

University/Undergrad

10 Terms

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Hormone is secreted by a an endocrine gland
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Hormone travels through the bloodstream to a target cell
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Hormone binds to a specific membrane receptor on the outside surface of the cell
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modified receptors bind with a G protein
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G protein is activated
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Activated G protein activates phosphidase
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\`phospholipase splits DIP 2 into DAG and IP3
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DAG activates protein kinases which causes phosphorlation of existing proteins
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IP3 triggers release of calcium from ER
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Calcium acts as an additional secondary messenger