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Cell cycle
Series of changes a cell undergoes from formation to reproduction
Centrosomes
Form the mitotic spindle during prophase
Interphase and mitotic phase
The two major periods of the cell cycle
Interphase
Period when the cell carries out routine activities and prepares for division
S (synthetic) phase
Phase of interphase when DNA replication occurs
New nuclear membranes
Form around each chromatin mass during telophase
Avascularity
Characteristic meaning epithelium lacks blood vessels
Apical surface
Faces the lumen or external environment
Tight junctions (zona occludens)
Junctions found on the lateral surface of epithelial cells
Simple cuboidal epithelium
Associated with absorption, secretion, and excretion
Diffusion from underlying connective tissue
How epithelium receives nourishment
Loss of apical-basal polarity and broken lateral contacts
Stimulates high regenerative capacities in epithelial cells
Simple columnar epithelium
Cells are taller than they are wide
Goblet cells
Mucus-secreting cells found in some epithelia
Pseudostratified columnar epithelium
Appears multilayered but is not, often with cilia and goblet cells
Endocrine glands
Release secretions into surrounding interstitial fluid
Stratified squamous keratinized epithelium
Type of epithelium covering thin skin
Keratinization
Provides protection from abrasion and dehydration
Microvilli and cilia
Associated with the apical surface
Thick skin
Found on the palmar and plantar surfaces of the hands and feet
Basement membrane
Layer separating epithelium from underlying connective tissue
Simple squamous epithelium
Single layer of flattened cells
Simple squamous epithelium
Facilitates transfer of gases, fluids, and nutrients due to its thinness
Stratified cuboidal epithelium
Most often found in ducts of exocrine glands
Anaphase
Phase in which centromeres split
Hemidesmosomes
Attach the basal surface of epithelial cells to the basement membrane
Cytokinesis
Begins during late anaphase and continues through mitosis
Contact inhibition
Normal cells stop dividing when they touch
G1 checkpoint (restriction point)
Most important checkpoint in the cell cycle
Endothelium
Epithelium lining blood vessels, the heart, and lymphatic vessels
G0 phase
Cells permanently cease dividing
Early prophase
Chromatin condenses into visible chromosomes
Centromere
Holds sister chromatids together
Functions of epithelium
Protection, Absorption, Filtration, Excretion, Secretion, Sensory reception
Metaphase plate
Imaginary plane midway between cell poles
Anaphase
Shortest phase of cell division
Stratified cuboidal epithelium
Most often has two layers of cells
Increased surface area for absorption
Primary characteristic of simple columnar epithelium with microvilli
Hormones
Messenger chemicals secreted by endocrine glands
Lymph or blood
Pathway endocrine secretions travel to reach target organs
Exocrine glands
Release secretions onto body surfaces or into body cavities
Exocrine glands
More numerous type of gland
Exocrine gland secretions
Mucous, sweat, oil, and saliva
Mucous cells and goblet cells
Important unicellular exocrine glands
Unicellular exocrine glands
Found in epithelial linings of intestinal and respiratory tracts
Mucin
Produced by mucous cells and goblet cells
Mucin
Sugar-protein that forms mucus
Simple glands
Have unbranched ducts
Compound glands
Have branched ducts
Tubular gland
Secretory cells form the duct
Alveolar glands
Secretory cells form sacs
Merocrine glands
Secrete products by exocytosis as they are produced
Merocrine gland secretions
Sweat and pancreatic secretions
Holocrine glands
Accumulate products within the cell, then rupture
Sebaceous oil glands
Example of a holocrine gland
Apocrine gland secretion
Products accumulate within the cell, but only the apex ruptures
Apocrine glands
Type of gland with controversial existence in humans
Alveolar glands
Glands with secretory cells forming sacs
Tubuloalveolar glands
Glands with both secretory cells forming ducts and sacs
Unicellular exocrine glands
Mucous cells and goblet cells
Multicellular exocrine glands
Sweat glands and salivary glands
Merocrine vs holocrine secretion
Merocrine uses exocytosis, holocrine involves cell rupture
Pancreas
Secretes its products by the merocrine method