Cardio DRUGS (Elsaid) - Exam 1

Phenylephrine

Alpha Adrenergic Receptor Agonist

α1 » α2

Vasopressor & nasal decongestant

Clonidine

Alpha Adrenergic Receptor Agonist

α2 > α1

Antihypertensive

Dexmedetomidine

Alpha Adrenergic Receptor Agonist

α2 » α1

Sedation

Norepinephrine

Mixed Alpha and Beta Adrenergic Receptor Agonist

α1 > β1

Vasopressor

Epinephrine 0.01-0.05 mcg/kg/min

Mixed Alpha and Beta Adrenergic Receptor Agonist

Predominant β (β1;β2) effect

Vasopressor & anaphylaxis

Epinephrine >0.05 mcg/kg/min

Mixed Alpha and Beta Adrenergic Receptor Agonist

α1>β1;β2

Vasopressor & anaphylaxis

Dobutamine

Beta Adrenergic Receptor Agonist

B1>B2»»»»A

Inotrope

Isoproterenol

Beta Adrenergic Receptor Agonist

B1=B2»»»»A

Inotrope

Albuterol

Beta Adrenergic Receptor Agonist

B2>B1»»»»A

Bronchodilator

Dopamine (LOW, 2-5 mcg/kg/min)

Adrenergic Receptor Agonist

D1

Dopamine (MED, 5-10 mcg/kg/min)

Adrenergic Receptor Agonist

B1 > A1

Increase CO, HR

Inotrope

Dopamine (HIGH, 10-20 mcg/kg/min)

Adrenergic Receptor Agonist

B1, A1

Increase SVR

Vasopressor

Prazosin, Terazosin, Doxazosin

Alpha Antagonist

A1>A2

Antihypertensive

Tamsulosin

Alpha Antagonist

A1>A2

Prostate tissue

Yohimbine

Alpha Antagonist

A2>A1

A2 Supplement, Stimulant (increases NE)

Labetalol and Carvedilol

Mixed Alpha and Beta Antagonists

B1=B2>A1>A2

CI: asthma (due to blocking B2, and thus block bronchodilation)

Metoprolol, Atenolol

Beta Antagonists

B1»B2

Propranolol

Beta Antagonists → Non-selective B blocker

B1=B2

CI: asthma

ACE-I drug ending name

-pril

ARB drug ending name

-sartan

Spironolactone

Aliskiren

Renin inhibitor

Furosemide

Loop diuretic

Ethacrynic acid

Loop diuretic to use in pt with SULFA ALLERGY