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Central Nervous System (CNS)
Brain and spinal cord
Peripheral Nervous System (PNS)
All nerves outside the CNS
Somatic Nervous System
Controls voluntary skeletal muscle movement
Autonomic Nervous System (ANS)
Controls involuntary bodily functions
Sympathetic Nervous System
Fight or flight; increases heart rate, dilates pupils, inhibits digestion
Parasympathetic Nervous System
Rest and digest; decreases heart rate, constricts pupils, stimulates digestion
Preganglionic neurotransmitter (ANS)
Acetylcholine (ACh)
Postganglionic Sympathetic neurotransmitter
Norepinephrine (NE)
Postganglionic Parasympathetic neurotransmitter
Acetylcholine (ACh)
Dorsal Root Ganglion
Contains sensory neuron cell bodies; damage causes loss of sensation
Law of Bell and Magendie
Dorsal = sensory input, Ventral = motor output
Hindbrain
Includes medulla, pons, cerebellum
Medulla
Controls breathing and heart rate
Pons
Sleep and relay functions
Cerebellum
Coordination and balance; damage causes uncoordinated movement
Midbrain
Contains superior and inferior colliculi
Superior Colliculus
Visual reflexes
Inferior Colliculus
Auditory reflexes
Forebrain
Largest brain region; includes cortex, thalamus, hypothalamus
Thalamus
Sensory relay station (except smell)
Hypothalamus
Hunger, thirst, temperature, hormones; controls pituitary gland
Meninges
Protective layers around CNS
Dura Mater
Outer tough layer of meninges
Arachnoid Mater
Middle web-like layer
Pia Mater
Inner delicate layer attached to brain
Ventricles
Four fluid-filled brain cavities
Lateral Ventricles
First pair of ventricles
Third Ventricle
Middle ventricle
Fourth Ventricle
Connects to spinal cord
Cerebrospinal Fluid (CSF)
Cushions brain, removes waste, provides buoyancy, maintains chemical stability
Choroid Plexus
Produces CSF
CSF Flow
Lateral → Third → Fourth → Subarachnoid space → blood
Basal Ganglia
Group of structures controlling movement
Direct Pathway
Increases movement (GO signal)
Indirect Pathway
Decreases movement (STOP signal)
Dopamine effect on Direct Pathway
Stimulates it (more movement)
Dopamine effect on Indirect Pathway
Inhibits it (less stopping)
Overall effect of dopamine
Increases voluntary movement
Parkinson’s Disease
Caused by low dopamine; tremor, rigidity, slow movement
Huntington’s Disease
Genetic disorder; uncontrolled movements, cognitive decline
Hypokinetic Disorder
Too little movement (e.g., Parkinson’s)
Hyperkinetic Disorder
Too much movement (e.g., Huntington’s)
Procedural Memory Deficit
Difficulty learning skills; linked to basal ganglia damage
Hippocampus
Forms new memories; damage causes inability to form new memories
H.M.
Famous patient with hippocampal damage and anterograde amnesia
Amygdala
Emotion processing (fear, aggression)
KlĂĽver-Bucy Syndrome
Amygdala damage; hypersexuality, no fear, overeating
Prefrontal Cortex
Decision-making, planning, personality
Prefrontal Damage
Poor judgment, personality change, impulsivity
Frontal Lobe
Movement, decision-making
Parietal Lobe
Touch and spatial awareness
Temporal Lobe
Hearing and memory
Occipital Lobe
Vision
Precentral Gyrus
Primary motor cortex
Postcentral Gyrus
Primary somatosensory cortex
Hemineglect
Ignore one side of space; usually right parietal damage
Prosopagnosia
Face blindness; temporal lobe damage
Cortical Blindness
Damage to occipital lobe
Cortical Deafness
Damage to temporal lobe
Language Lateralization
Left hemisphere dominant for language
Music/Emotion Lateralization
Right hemisphere dominant