pKa Values

Oxygen Acids; HO-H:

14.00

Oxygen Acids; H2O+-H:

0

Oxygen Acids; Me-O+-H2:

-2.2

Oxygen Acids; tBu-OH:

17

Oxygen Acids; CH3-OH:

15.5

Oxygen Acids; Ph-OH:

9.95

Oxygen Acids; HOO-H:

11.6

Weak Acids; R3C-H:

55

Weak Acids; C=C:

42

Weak Acids; H-H:

35

Weak Acids; CH4:

48

Weak Acids; Ph-H:

43

Weak Acids; R-=-H:

25

Weak Acids; H2C=CH-CH3:

43

Weak Acids; PhCH3:

41

Strong Acids; HBr:

-9

Strong Acids; HCl:

-8

Strong Acids; HO3SO-H:

-3

Strong Acids; CH3Ph-SO3-H:

-3

Miscellaneous; Br3C-H:

13.7

Miscellaneous; RS-H:

10.5

Miscellaneous; PhS-H:

6.5

Miscellaneous; H-CN:

9.4

Miscellaneous; Ph3P+CH3:

22.4

Ammonium Ions; O2N-Ph-NH3+:

1.0

Ammonium Ions; Ph-NH3+:

4.62

Ammonium Ions; Pyridine:

5.2

Ammonium Ions; Piperidine:

11.2

Ammonium Ions; H3N+-H:

9.2

Ammonium Ions; iPr2N-H:

35

Ammonium Ions; H3C-=N-H:

-10

Carboxylic Acids; CH3CO2H:

4.74

Carboxylic Acids; F3CCO2H:

0.2

Carboxylic Acids; HCO2H:

3.75

Carboxylic Acids; PhCO2H:

4.2

Carboxylic Acids; CO3H:

10.3

Protonated Carbonyls; PhC(OH)2:

-7.8

Protonated Carbonyls; CH3COHOR:

-6

Protonated Carbonyls; (CH3)2COH:

-6

Protonated Carbonyls; PhCOHCH3:

-6.2

Protonated Carbonyls; CH3COHNH2:

-1

Deprotonation Alpha to Carbonyl; H-CH2COCH3:

20

Deprotonation Alpha to Carbonyl; H-CH2COH:

17

Deprotonation Alpha to Carbonyl; CH2COHCH3:

11

Deprotonation Alpha to Carbonyl; CH3CONH2:

15

Deprotonation Alpha to Carbonyl; H-CH2CO-OtBU:

24.5

Deprotonation Alpha to Carbonyl; H-CH2CONMe2:

35

Active Methylene Compounds; CH3COCH2COCH3:

9

Active Methylene Compounds; CH3COCH2CO-OEt:

11

Active Methylene Compounds; OEt-COCH2CO-OEt:

13

Active Methylene Compounds; N=CH2=N:

11.1

Active Methylene Compounds; isoindole-1,3-dione:

8.3