Micro Exam 4: Lec 2: Viruses, Virions, Prions

Ebola

helical virus, enveloped, RNA,

Ebola has a link to what animal

bats

What book came out in 1989 in Rustin Virginia about monkeys with Ebola and why didn’t it spread in the US

the hotstone, strand of ebola only affected monkeys

Why is HIV dangerous

it acts on immune system

HIV infects

helper T cells

People with AIDS die from

secondary infections bc immune system is hijacked

HIV

enveloped, RNA

HIV replication

virus comes in contact with cell membrane, and whole virus can get absorbed into cell, gets into the nucleus of eukaryotic

SARS virus not seen since

2004

Only symptom all patients had in common for SARS

fever above 100.4

Covid 19 can spread

before a person even shows symptoms

How do you tell covid from flu

if you have difficulty breathing its covid, if you’re sneezing a lot its flu

How do you tell covid from a cold/URI

dry cough, difficulty breathing, diarrhea—covid. sneezing and stuffy nose is cold

how do you tell covid from allergies

fever, aches, sore throat, diarrhea—covid. sneezing, stuffy nose, watery eyes—allergies

What were Davidsons symptoms when he had covid

difficulty breathing, lost of taste and smell

Do pfizer and Moderna have the actual virus

no it’s mRNA that creates a protein to combat that

The viral vector

has a different virus to do the same

Difference between mRNA and vector

delivery system being mRNA or vector

Can you get covid from mRNA vaccine

no

Prions are only

infectious protein no genetic material

Where is the prion and what does it do

in the brain and folds it abnormally

Is there a cure for prion disease

no you will die

What’s mad cow disease

Bovine spongiform encephalopathy

Chronic wasting disease CWD impacts

deer

Prion theory

infected prion protein can touch regular proteins and turn them into prions

CJD is

prion disease of people having issues with memory.

What are the forms and causes of CJD of each

classical/sporadic: unknown, familial: inherited mutation, Iatrogenic: contamination of brain during surgery, variant: exposure to BSE

Connection of CJD and BSE

If a cow has BSE and you eat it you will get the variant of CJD

Kuru is a disease amongst

cannibals

Kuru was discovered by who and when

Robert and Louise Glasse in 1950

Kuru made the fore tribe dead always within

2 years

Endocannibalism

when a family member dies and the family eats them

Viroids

only made up of genetic material ssRNA, no protein coat, little larger than prions, mostly in plants

How do viroids spread

through contact between plants