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Chargaff’s Rule
In any species, the number of A and T bases are equal and the number of G and C bases are equal
DNA structure
double helix modeled by watson and crick
phosphate, deoxyribose, and N-base (A, T, G, C)
1 DNA nucleotide =
complementary and antiparallel
Two characteristics of DNA
50 million base pairs
average chromosome length
10,000 bp
average gene length
1 protein
1 gene encodes for
origin of replication (ori)
starting points of DNA replication
1
bacterial chromosomes have how many ori?
100-1,000
eukaryotic chromosomes have how many ori?
replication fork
a y shaped region where new DNA strands are elongating at the end of each replication bubble
helicases
enzymes that untwist the double helix at replication forks
helicase
primase
DNA pol III
DNA pol I
Ligase
enzymes involved in DNA replication