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what are key clinical manifestations of depression?
anergia
anhedonia
anxiety
sluggishness
vegetative findings
thoughts of suicide
what is anergia?
low energy
what is anhedonia?
loss of interest or pleasure in things once enjoyed
what are vegetative findings in depression? *
changes in eating & sleeping
low energy
poor concentration
changes in daily behavior
low self-esteem
changes in bowel habits
decreased interest in sexual activity
what psychomotor changes can happen in depression? *
psychomotor agitation (restlessness)
psychomotor retardation (slowed movement, speech, responses)
what physical assessment findings can be seen in depression?
psychomotor retardation (slowness, stumped posture)*
psychomotor agitation (restlessness, pacing, finger tapping)*
sad mood with blunted affect
poor grooming or hygiene
social isolation
slowed speech, delayed responses
what does psychomotor retardation look like? *
slowness, slumped posture, slowed speech, and delayed responses
what does psychomotor agitation look like? *
restlessness, pacing, and finger tapping
what medication classes are used to treat depressive disorders?
selective serotonin reuptake inhibitors (SSRIs)
serotonin norepinephrine reuptake inhibitors (SNRIs)
tricyclic antidepressants (TCAs)
monoamine oxidase inhibitors (MAOIs)
second-generation antipsychotics (SGAs)
mood stabilizers
anticonvulsants (anti-epileptic agents)
what food interaction can happen with monoamine oxidase inhibitors? *
tyramine can cause hypertensive crisis
what nonpharmacologic treatments are used for depression?
cognitive behavioral therapy (CBT)
electroconvulsive therapy (ECT)
transcranial magnetic stimulation (TMS)
how does cognitive behavioral therapy help treat depression?
it helps change behavior by changing thinking
when is electroconvulsive therapy used for depression?
it is used for treatment-resistant depression, when medications are not working, or when the client is highly suicidal
how is transcranial magnetic stimulation different from electroconvulsive therapy?
it uses magnetic pulses and does not require anesthesia, so it is less invasive