Systemic Diseases with Oral Manifestations

These flashcards cover systemic diseases and their oral manifestations as outlined in the lecture notes.

Leukemia

Malignant tumors of white blood cells (WBC) that may have normal or below normal WBC counts. Oral findings include mucosal enlargement, bleeding, and necrosis.

Agranulocytosis

A reduction in granular leukocytes, especially neutrophils, leading to oral lesions such as gangrenous ulceration.

Anemia

A deficiency of erythrocytes and hemoglobin, resulting in various forms like iron deficiency anemia, pernicious anemia, folic acid deficiency anemia, and hemolytic anemia.

Plummer Vinson Syndrome

A symptom complex in middle-aged females causing stomatitis, dysphagia, and oral lesions such as leukoplakia.

Erythroblastosis Fetalis

A hemolytic disease in newborns due to blood group incompatibility; can result in oral pigmentation.

Thalassemia (Cooley's Anemia)

A congenital disease affecting hemoglobin synthesis; characterized by facial and dental abnormalities.

Dwarfism

Hypofunction of the pituitary gland resulting in delayed eruption of teeth and maxillary and mandibular underdevelopment.

Gigantism

Caused by excess growth hormone, leading to oral manifestations like enlarged maxilla, mandible, and macrodontia.

Acromegaly

Occurs after growth cessation, causing enlarged maxilla and mandible along with oral health issues such as diastemas.

Hyperparathyroidism

A disorder characterized by increased blood calcium, leading to diffuse bone loss and oral manifestations.

Addison’s Disease

Chronic adrenal insufficiency resulting in weakness and oral pigmentation.

Hyperthyroidism

Excessive thyroxine secretion leading to a high metabolic rate and early eruption of teeth.

Hypothyroidism

Low metabolism associated with thyroid issues; childhood onset leads to cretinism.

Cretinism

Childhood hypothyroidism marked by short stature and delayed development.

Myxedema

Adult hypothyroidism characterized by fatigue and oral manifestations like thickened lips.

Paget's Disease

Generalized bone disease that causes alveolar ridge enlargement and possible tooth migration.

Fibrous Dysplasia

A bone disease in childhood associated with skin spots and jaw enlargement.

Leontiasis Ossea

A form of fibrous dysplasia affecting the upper face with hyperostosis.

Caffey's Disease

Infant-like cortical hyperostosis characterized by bone enlargement in young children.

Hypercementosis

Excessive buildup of cementum on the roots of teeth, commonly noted in gigantism.

Osteitis Fibrosa Cystica Generalisata

A condition also known as hyperparathyroidism, leading to bone changes in the jaw.

Ground Glass Appearance

Radiographic finding in hyperparathyroidism indicative of diffuse bone loss.

Microscopic Appearance of Paget's Disease

A characteristic mosaic pattern resulting from bone destruction and apposition.

osteitis fibrosa cystica generalisata or von

reclinghausens disease

What is the other name of hyperparathyroidism

FIBROUS DYSPLASIA

disease of childhood and adolescence, sometime associated with hypergonadism and with brown spot on the skin, cafe au lait spots