Side Effects, Adverse Effects & Allergies✅

SSRIs black box warning?

Suicidal ideation in <24 yrs (BLACK BOX)

Opioids + Benzos risk?

Respiratory depression, death (BLACK BOX)

Statins major risk?

Rhabdomyolysis → muscle breakdown → kidney failure

ACE Inhibitors serious side effect?

Fluoroquinolones risks?

Tendon rupture, QT prolongation, peripheral neuropathy

Methotrexate toxicity risks?

Hepatotoxicity, bone marrow suppression, pulmonary toxicity

Clozapine (Clozaril) major risk?

Agranulocytosis → requires WBC monitoring

Isotretinoin major risk?

Teratogenic (severe birth defects)

Amiodarone toxicities?

Pulmonary toxicity, thyroid dysfunction, photosensitivity

Heparin serious adverse effect?

HIT (Heparin-Induced Thrombocytopenia)

Common side effects for ACE Inhibitors

Dry cough (very common), hyperkalemia, first-dose hypotension

Common side effects for Beta Blockers

Bradycardia, fatigue, cold extremities, erectile dysfunction

Common side effects for Statins

Myalgia (muscle pain), elevated liver enzymes

Common side effects for SSRIs

Sexual dysfunction, insomnia, GI upset, weight changes

Common side effects for Metformin

GI upset (nausea, diarrhea), lactic acidosis (rare)

Common side effects for Diuretics (loop)

Hypokalemia, dehydration, ototoxicity (furosemide high doses)

Common side effects for NSAIDs

• GI ulcers/bleeding, renal impairment, fluid retention, increased BP

Common side effects for Opioids

Constipation, sedation, nausea, respiratory depression

Common side effects Corticosteroids (long-term)

Hyperglycemia, osteoporosis, weight gain, immunosuppression, Cushing's syndrome

Common side effects Antihistamines (1st gen)

Sedation, dry mouth, urinary retention, constipation