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Describe the structure of haemoglobin. (2)
Quaternary Structure protein
4 iron ions
Describe the role of haemoglobin in loading, transporting and unloading oxygen. (5)
• Haemoglobin binds to oxygen
• At high partial pressures of oxygen
• Binding to one oxygen makes binding to other oxygens easier
• Oxygen transported as oxyhaemoglobin
• Haemoglobin unloads oxygen at the respiring tissues
• At low partial pressure of oxygen
Describe properties of iron that allows it to perform its role in red blood cells. (3)
• It is charged or polar
• Forms part of haemoglobin
• Binds to oxygen
Describe and explain the Bohr shift.(3)
• Increased carbon dioxide concentration lowers blood pH
• So greater dissociation of oxygen
• For aerobic respiration in tissues
Explain why blood pH decreases in active tissues. (3)
• Aerobic respiration produces carbon dioxide
• Carbon dioxide dissolves in blood forming carbonic acid
• Acid dissociates forming more hydrogen ions
Explain the advantage of different shaped oxygen dissociation curves. (4)
• Right-shifted curves for reduced affinity
• More unloading into respiring tissues for high metabolism
• Left-shifted curves for greater affinity
• More loading of oxygen in low-oxygen environments
Explain why affinity of haemoglobin increases when a molecule of oxygen binds to it. (2)
• Binding of oxygen causes shape change
• Causing another binding site to be exposed
Define partial pressure. (1)
• Concentration of a gas
Describe the path of blood through the heart. (6)
• From vena cava into right atrium
• Through atrioventricular valves into right ventricle
• Through semi lunar valves into pulmonary artery
• From pulmonary vein into left atrium
• Through atrioventricular valves into left ventricle
• Through semi lunar valves into aorta
Name the blood vessels that bring blood to and from the kidneys. (1)
• Renal artery and renal vein
Explain why atrioventricular valves open and close. (2)
• Atrioventricular valves open when atrial pressure is greater than ventricular pressure
• Atrioventricular valves close when ventricular pressure is greater than atrial pressure
Explain how the features of an aorta are related to its function. (4)
• Smooth muscle absorbs high pressure
• Elastic tissue stretches and recoils to maintain blood pressure
• Endothelium reduces friction
• Protein coat prevents artery wall splitting
Explain how the structure of a vein is related to its function. (2)
• Thinner wall since lower blood pressure
• Valves to prevent backflow
Explain how blood in a vein is returned to the heart. (6)
• Muscles around vein contract and press on vein and squeeze blood through
• Valves to backflow
• Heart systole pushes blood through veins • During diastole recoil of heart
• Draws blood from veins into atria
• Wide lumen and low friction
Explain how the structure of a capillary is adapted for exchange of substances. (4)
• Permeable capillary lining
• Single cell thick so short diffusion distance
• Flattened endothelial cells so short diffusion distance
• Narrow lumen so large surface area to volume ratio
• Narrow lumen so decreased flow rate and more time for diffusion
Explain how tissue fluid forms. (2)
• High hydrostatic pressure at arterial end
• Forces water and ions out of capillaries
Explain how water from tissue fluid is reabsorbed. (4)
• Proteins remain in the blood
• Creating a water potential gradient
• Water moves into blood by osmosis
• Or drains into the lymphatic system
Explain how an arteriole can reduce blood flow into capillaries. (2)
• Smooth muscle contracts
• Constricts arteriole
Explain how the structure of xylem is suitable to its function. (3)
• Forms hollow tubes with no end walls so allows continuous column of water
• No cell organelles or cytoplasm so no obstruction of water flow
• Cell walls made of lignin so withstands tension in the column
• Cell walls made of lignin so withstands tension in the column caused by transpiration and adhesion
Explain how water moves up xylem vessels by the cohesion-tension theory. (4)
• Transpiration
• Decreased water potential creates tension at the top of the xylem
• Hydrogen bonds cause cohesion between water molecules
• Maintains continuous water column
• Adhesion between water molecules and xylem walls by hydrogen bonds
Explain how sucrose is transported by mass flow. (6)
• Sucrose is actively transported into phloem sieve element
• By a companion cell
• Lowering water potential of the phloem sieve element
• Water moves into the sieve element by osmosis
• Increasing hydrostatic pressure
• Sucrose is metabolised at the sink cells
Explain how companion cells are adapted for the functions. (2)
• Lots of mitochondria to produce ATP for active transport
• Lots of carrier proteins to actively transport sucrose into phloem sieve elements