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Q: What is atherosclerosis?
A: A disease characterized by the buildup of lipids, fibrous tissue, inflammatory cells, and calcification within the arteries.
Q: What triggers plaque buildup in atherosclerosis?
A: Endothelial damage causing chronic inflammation.
Q: What is the leading fatal result of atherosclerosis?
A: Cardiovascular disease.
Q: What imaging method provides detailed analysis of plaque surfaces and composition?
A: B-mode imaging.
Q: Where does carotid plaque most commonly form?
A: At the carotid bifurcation, distal CCA, proximal ICA, and proximal ECA.
Q: In early plaque formation, what thickens first?
A: The intima-media layers.
Q: What may form between the plaque and the lumen in early plaque development?
A: A fibrous cap.
Q: What does B-mode ultrasound measure in the carotid arteries?
A: Intima-media thickness (IMT).
Q: What three locations are used to measure IMT?
A: Common carotid artery, bifurcation, and internal carotid artery.
Q: What CIMT measurement is considered abnormal?
A: Greater than 0.9 mm.
Q: Elevated IMT is considered what kind of sign?
A: An early warning sign of vascular damage.
Q: Does IMT represent true atherosclerosis?
A: No, it is mainly a marker of vascular aging.
Q: Small intima-media thickening is common in what age group?
A: People older than 50 years old.
Q: What factors affect ultrasound plaque assessment quality?
A: Sonographer expertise, image quality, vascular segment examined, and plaque characterization.
Q: What type of images should be acquired when evaluating plaque?
A: Accurate 2D longitudinal and transverse images, and 3D images if possible.
Q: Why must plaque be evaluated in both transverse and sagittal planes?
A: Because plaque is irregular and may not be fully visualized in one plane.
Q: Which ultrasound view is most important for gray-scale plaque assessment?
A: The transverse view.
Q: Why is longitudinal estimation of stenosis unreliable?
A: It can underestimate or overestimate plaque severity.