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Whole blood for testing in a clinical laboratory is usually collected from
- a capillary.
- a deep artery.
- a superficial vein.
- a superficial artery.
- a deep vein.
- a superficial vein.
Which plasma protein transports fatty acids and some hormones?
- steroid-binding protein
- gamma globulin
- apolipoprotein
- hormone-binding protein
- albumin
- albumin
The most abundant proteins in blood plasma are
- albumins.
- transport proteins.
- lipoproteins.
- fibrinogens.
- globulins.
- albumins.
Blood that has clotting proteins removed is termed
- serum.
- formed elements.
- whole blood.
- hematocrit.
- plasma.
- serum.
You have spent 24 hours traveling from the U.S to New Zealand, on quite a few airplanes with many stops. Because of the stress, changes in time zones, and short blocks of time between planes, you find yourself tired with a headache when you arrive. You are severely dehydrated. A hematocrit value of your blood would be ________ than normal because ________.
- lower; you have less blood plasma volume
- lower; the bone marrow is making fewer red blood cells due to the latitude of the airplanes
- lower; more red blood cells are being made by the bone marrow
- higher; you have less blood plasma volume
- higher; more plasma proteins are made by the liver
- higher; you have less blood plasma volume
Each molecule of heme contains a single ion of what element? (Figure 19-3)
- calcium
- potassium
- magnesium
- iron
- sodium
- iron
Jane has been taking the antibiotic chloramphenicol for a few weeks as treatment for a serious bacterial infection. There is a possibility that a future side effect of long-term antibiotic therapy could affect the bone marrow leading to severe changes in her hematocrit. The result is
- pernicious anemia.
- thrombocytopenia.
- aplastic anemia (failure to produce red blood cells).
- erythroblastosis.
- drug resistance
- aplastic anemia (failure to produce red blood cells).
All the circulating red blood cells in a healthy adult originate in the
- heart.
- spleen.
- lymph tissue.
- thymus.
- red bone marrow.
- red bone marrow.
Surgical removal of the stomach could cause
- pernicious anemia.
- leukocytosis.
- jaundice.
- thrombocytopenia.
- hemophilia.
- pernicious anemia.
Eileen is a strict vegan and therefore eats no animal products. She develops an anemia that her doctor thinks is caused by a nutritional deficiency. Which of the following is the likeliest candidate?
- vitamin B6 deficiency
- sickle cell anemia
- aplastic anemia
- vitamin K deficiency
- iron-deficiency anemia
- iron-deficiency anemia
is a condition in which the oxygen-carrying capacity of the blood is reduced.
- Polycythemia
- Anemia
- Thrombocytopenia
- Leukemia
- Leukopenia
- Anemia
A bruise appears as a greenish spot in the skin because
- the heme group in the hemoglobin has broken down into biliverdin.
- dead white blood cells accumulate at the site of injury.
- red blood cells lyse releasing biliverdin from inside.
- hemoglobin has leaked from the blood into the injury.
- bilirubin from iron recycling has built-up in the bruise.
- the heme group in the hemoglobin has broken down into biliverdin.
The waste product bilirubin is produced from
- globin chains of hemoglobin.
- heme molecules plus iron.
- abnormal proteins found in red blood cells.
- iron found in hemoglobin molecules.
- heme molecules lacking iron.
- heme molecules lacking iron.
are immature erythrocytes that are present in the circulation.
- Normoblasts
- Erythroblasts
- Band cells
- Myeloblasts
- Reticulocytes
- Reticulocytes
Mrs. Higgins needs to have major surgery. Two weeks before the surgery, her doctor prescribes EPO. Which of the following statements best explains his reason for doing this?
- After she takes EPO, Mrs. Higgins's risk of infection will go down because of increased production of WBCs.
- By prescribing EPO, the doctor will decrease her hematocrit so that her blood is less likely to clot during surgery.
- By prescribing EPO, the doctor can stimulate Mrs. Higgins's body to produce an overabundance of RBCs, which can be harvested and saved for her surgery.
- By prescribing EPO, the doctor will be able to increase oxygen levels because EPO causes hemoglobin to bind oxygen more efficiently.
- By prescribing EPO, the doctor can stimulate Mrs. Higgins's body to produce an overabundance of RBCs, which can be harvested and saved for her surgery.
Red blood cells carry __________ to the lungs and __________ to the tissues.
- oxygen; nutrients
- carbon dioxide; oxygen
- nutrients; carbon dioxide
- oxygen; carbon dioxide
- carbon dioxide; oxygen
Antigens of the surface of red blood cells are also called ________ and antibodies in the blood plasma are also called ________.
- erythrogens; antibiotics
- T-cells; B-cells
- serum; plasma
- agglutinins; agglutinogens
- agglutinogens; agglutinins
- agglutinogens; agglutinins
The clumping of red blood cells, when the specific antibody against the antigen on the cells is added, is called
- hemostasis.
- vascularization.
- agglutination.
- areolation.
- coagulation.
- agglutination.
In an emergency situation when you have no time to wait for cross-matched blood you could give a patient type ________ until the cross-match is available.
- O positive
- AB positive
- O negative
- AB negative
- O negative
White blood cells that are increased in individuals having an allergic reaction are the
- monocytes.
- neutrophils.
- platelets.
- eosinophils.
- lymphocytes.
- eosinophils.
The most numerous WBCs in a differential count of a healthy individual are
- leukocytes.
- monocytes.
- neutrophils.
- basophils.
- lymphocytes.
- neutrophils.
Which of these descriptions best matches the term B lymphocytes?
- often elevated in allergic individuals
- helper cells are one type
- kill bacteria using hydrogen peroxide
- develop into plasma cells and produce antibodies in response to antigens
- adhere to collagen beneath endothelium
- develop into plasma cells and produce antibodies in response to antigens
Which of these descriptions best matches the term T lymphocytes?
- often elevated in allergic individuals
- adhere to collagen beneath endothelium
- kill bacteria using hydrogen peroxide
- are involved in cell mediated immunity
- develop into plasma cells and produce antibodies in response to antigens
- are involved in cell mediated immunity
The blood cells involved in specific immunity are the
- lymphocytes.
- neutrophils.
- basophils.
- monocytes.
- erythrocytes.
- lymphocytes.
A patient has an infected puncture wound to her foot. Which type of white blood cell would you expect to be elevated in a differential white cell count?
- basophils
- lymphocytes
- monocytes
- neutrophils
- eosinophils
- neutrophils
Antihistamines would work best against which type of WBC?
- neutrophil
- eosinophil
- basophil
- monocyte
- basophil
The function of platelets is to assist in the
- process called hemostasis.
- transport of blood gases such as oxygen.
- removal of worn out red blood cells.
- destruction of bacteria.
- immune response during an infection.
- process called hemostasis.
A sign of thrombocytopenia would be
- bleeding.
- bacterial infections.
- excessive clotting.
- allergic reactions.
- a drop in oxygen-carrying capacity.
- bleeding.
An important function of platelets is to __________.
- transport nutrients
- transport blood gases
- transport thrombopoietin
- transport clotting factors
- transport clotting factors
involves a cascade of reactions leading to the conversion of fibrinogen to fibrin.
- The platelet phase
- Vascular spasm
- Coagulation
- Fibrinolysis
- Retraction
- Coagulation
The extrinsic pathway of coagulation is initiated by the
- release of tissue factor (Factor III).
- sticking of platelets to damaged tissue.
- conversion of prothrombin to thrombin.
- release of heparin from the liver.
- activation of Factor VII exposed to collagen.
- release of tissue factor (Factor III).
The intrinsic pathway of coagulation is activated by the
- conversion of prothrombin to thrombin.
- activation of Factor XII by platelet factors.
- release of tissue factor (Factor III).
- release of heparin from the liver.
- sticking of platelets to each other.
- activation of Factor XII by platelet factors.
Some rat poisons contain a toxin that blocks the liver's ability to utilize vitamin K. Animals that consume this poison would die of
- acidosis.
- anemia.
- thrombocytopenia.
- hemorrhage.
- starvation.
- hemorrhage.
A moving blood clot is called a(n)
- thrombus.
- procoagulant.
- plaque.
- platelet plug.
- embolus.
- embolus.
The common pathway in coagulation ends with __________.
- release of PF-3
- conversion of soluble fibrinogen to insoluble fibrin
- adhesion of platelets to a damaged vessel wall
- positive feedback of thrombin formation
- conversion of soluble fibrinogen to insoluble fibrin
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