Gluconeogenesis

step 1

pyruvate to oxaloacetate

step 1 enzyme

pyruvate carboxylase

step 1 details

also uses: CO2, ATP, H2O

produces: ADP, Pi, 2H+

step 2

oxaloacetate to phosphoenolpyruvate

step 2 enzyme

phosphoenolpyruvate carboxykinase

step 2 details

also uses: GTP

produces: CO2, GDP

step 3

phosphoenolpyruvate to 2-phosphoglycerate

step 3 enzyme

enolase

step 3 details

also uses H2O

step 4

2-phosphoglycerate to 3-phosphoglycerate

step 4 enzyme

phosphoglycerate mutase

step 5

3-phosphoglycerate to 1,3-bisphosphoglycerate

step 5 enzyme

phosphoglycerate kinase

step 5 details

uses: ATP

produces: ADP

step 6

1,3-bisphosphoglycerate to glyceraldehyde-3-P

step 6 enzyme

glyceradehyde-3-P dehydrogenase

step 6 details

uses: NADH, H+

produces: NAD, Pi

step 7

glyceraldehyde-3-P to dihydroxyacetone phosphate

step 7 enzyme

triose phosphate isomerase

step 8

glyceradlehyde-3-P and dihydroxyacetone phosphate to fructose-1,6-BP

step 8 enzyme

aldolase

step 9

fructose-1,6-BP to fructose-6-P

step 9 enzyme

fructose-1,6-biphosphatase

step 9 details

also uses: H2O

produces: inorganic phosphate

step 10

fructose-6-P to glucose-6-P

step 10 enzyme

phosphoglucose isomerase

step 11

glucose-6-P to glucose

step 11 enzyme

glucose-6-phosphatase

step 11 details

uses: H2O

produces: inorganic phosphate