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What is sex?
biologically determined
Who has larger gametes?
females
Who has small gametes?
males
What chromosomes do females have?
XX
What chromosomes do males have?
XY
How many people fall into one of these two sex categories (XX or XY)?
98.3%
How many people have a chromosomal anomaly, but present as either male or female?
1.6%
How many people are intersex?
0.01%
What is gender?
social construct; society’s definiton of masucline and feminine (personal identity)
What is chromosmal sex?
XX
What is genotypic sex?
SRY or not
What is 45, X?
turner syndrome
What is the gonadal phenotype of turner syndrome?
streak ovaries, no puberty, impaired fertility
What are clinical concerns of turner syndrome?
caardiac & renal defects, lymphedema
What is 47, XXY?
Klinefelter syndrome
What is the gonadal phenotype of klinefelter syndrome?
small testes, delayed/incompleted puberty, imapired fertility
What are the clinical concerns of Klinefelter syndrome?
breast cancer, learning disabilities
What is 45 X, 46 XY?
mixed gonadal dysgenesis
What is the gonadal phenotype of mmixed gonadal dysgenesis?
streak ovary & testis, incomplete puberty, impaired fertility
What are clinical concerns of mixed gonadal dysgensis?
cardiac & renal defects
What is 46 XX, 46 XY?
chromosomal ovotesticular
What is the gondadal phenotype of chromsomal ovotesticular?
testicular & ovarian tissue present
What are the clinical concerns of chromosomal ovotesticular?
hyospadias, cryptorchidism
What is the SRY gene?
sex-determining region Y; present on male chromosomes
What does SRY drive?
expression of testosterone and DHT
What is androgen sensitivity?
how strongly a person’s cells respond to androgen hormones (ex. testosterone)
What is phenotypic sex?
expression of male or female anatomy
What is internal phenotypic sex?
presence of testes or ovaries
What is external phenotypic sex?
genitalia
What are the functions of reproductive organs?
pleasure, bonding, exploration, stress relief
What are the parent cells of mitosis?
2n
What are the daughter cells of mitosis?
2 daughter cells (2n)
What is the division of mitosis?
one division
What are the parent cells of meiosis?
2n
What are the daughter cells of meiosis?
2 daughter cells (2n)
What is the division of meiosis?
daughter cells each divide
What are the gametes of meiosis?
4 (In)
What is gametogenesis
creation of gametes
What is the first step of gamete formation?
stem cell (gametogonia) replication
What is the second step of gamete formation?
meiosis
What is the third step of gamete formation?
gamete maturation
When does gametogenesis begin (males and females)?
before birth
When is gametogensis completed (males and females)?
after puberty
What is gametogonia?
stem cells located within the gonads that act as the precursors to sex cells (gametes)
When does gametogonia mitosis begin in females?
week 7
When does gametogonia end in females?
week 20-22
When does gametogenesis meiosis begin in females
prophase I, week 22
When is gametogenesis meiosis completed in females?
meiosis II after contact with sperm
When does gametogonia mitosis begin in males?
week 7-8
When is gametogonia mitosis completed in males?
never; continues through life
When does gametogensis meiosis begin for males?
puberty
When is gametogenesis meiosis completed in males?
never; continues through life
What is oogenesis?
biological process of creating female gametes (ova or eggs) in the ovaries
What are female stem cells?
oogonia
When is oognia present?
developing fetus going through mitosis
When is oogenesis meiosis I completed?
prior to ovulation
When is oogeneis meiosis II completed?
after interaction with sperm
What is cytokinesis during oogenesis meiosis I and II?
unequal; into daughter oocytes
What are polar bodies?
smaller cell of cytokinesis; non-viable during meiosis I and II
What does cytokinesis result in?
1 larger cell, 1 small cell (aka polar body)
What do polar bodeis contain?
DNA; do not go through further splitting
What is spermatogenesis?
biological process of creating mature male sperm cells (spermatozoa) within the testes
What are the types of spermatogenesis?
Type A and type B
What is type A spermatogonia?
stem cell that undergoes mitosis to divide into further type A cells or type B spermatogonia
What is type B spermatogonia?
undergo mitosis and further differentiate into primary spermatocytes, enter meiosis
What are male stem cells?
spermatagonia
What is spermatogonia?
stem cells that produce sperm; go through two mitotic divisions
What is Meiosis I in spermatogenesis?
primary spermatocyte divides into secondary spermatocytes
What is meiosis II in spermatogenesis?
secondary spermatocyte divides into spermatids
What is spermiogenesis?
spermatids develop into sperm
What connects round spermatid?
cytoplasmic bridge (share the cytoplasm equally)
How long does spermatogenesis (formation of sperm) take?
approx. 74 days (60-80 day timeline)
What is spermiogenesis?
transformation into sperm; final stage of spermatogenesis
What is the result of spermiogenesis?
gain midpiece, flagellum, and acrosome
What is the flagellum?
tail of the sperm
What is the acrosome?
filled with proteases (enzymes) needed for fertilization; protects the oocyte
What organelles remain during spermiogenesis?
nucleus, centriole, mitochondria
What makes up the head of sperm?
acrosome and nucleus
What makes up the mid-piece of sperm?
centrioles and mitochondria
What makes up the tail of sperm?
flagellum and microtubules
What are gonads?
produce gametes
What are copulation organs?
physical contact, stimulation, and lubrication during intercourse
What are the kinds of copulation organs?
sensory and secretory organs
What are sensory organs?
specialized structures that detect stimuli from the environment and send signals to the brain
What are secretory organs?
organs or glands produce and release substances like hormones, enzymes, or fluids
What is part of the female reproductive anatomy?
ovaries, uterine tubes, uterus, vagina, accessory glands
What are ovaries?
female gonad; produce oocytes/gametes
What are uterine tubes?
aka fallopian tubes; move into the uterus
What is the function of the uterus?
gestation
What is the function of the vagina?
copulation and parturition (giving birth)
What are the parts of the ovary?
cortex and medulla
What is the ovary cortex tissue?
simple cuboidal epithelium
What is the ovary cortex?
developing follicles, remnants of ovulated follicles
What is the ovary medulla?
blood vessels and nerves
What are ovarian follicles?
small, fluid-filled structures inside the ovaries that contain and support immature egg cells (oocytes)
How long does maturation from primodrial to tertairy follicle take?
300 day period
What is a follicle?
oocyte + nourishing cells
What does FSH secretion stimualte?
follicle growth into different stages
What is aromatase?
converts androgens into estrogens
What makes up the primordial follicle?
arrested oocyte and pre-granulosa cells