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What is Health? (according to WHO)
"A state of complete physical, mental and social wellbeing and not merely the absence of disease and infirmity"
What are the dimensions of Wellness?
Physical
Intellectual
Emotional
Social
Spiritual
Vocational/occupational
Financial
Environmental
What are the aspects that determine a quality of life?
Absence of chronic disease
Mental Functioning and prevention of cognitive decline
Physical strength and fitness
Aerobic fitness
Emotional health
Spirituality
Risk factor
The longer you life, the more likely you are to live ________. (ex. if you live to 65, you have a higher chance of living __________)
longer
What is the average currently life expectancy @ birth in the US?
76.4
What is the average lifespan of women in the US?
79.3
What is the average lifespan of men in the US?
73.5
2020/COVID-19 marked the first _________ in population since 1920 (the spanish flu)
dip
Around what number does the US fall when ranked on life expectancy?
~47
What is a “blue zone”?
Areas with a longer life span (100 yrs +)
What are the 5 blue zone locations?
Okinawa, Japan
Sardinia, Italy
Nicoya Peninsula, Costa Rica
Icaria, Greece
Loma Linda, CA
Blue zones: scientific or speculative?
More speculative, recent data casts some doubt
Compression of Morbidity:
Compression of the period between an increasing average age of onset of disability and the age of death
How does chronic disease influence morbidity and mortailty?
Declines both, lowers quality of life
What are the top 5 leading causes of death for 2022 in the US?
Heart disease
Cancer
Accidents/Injuries
COVID-19
Storke
What is a Chronic Disease?
Definition varies by data used and disciple of researchers
CDC suggest that broadly, a chronic disease lasts more than a year
“Ongoing medical attention or limit daily activities
Long duration, slow progression
Causes of Chronic Disease:
Underly determination of chronic disease
socioeconomic, cultural, political, environmental
Modifiable factors
unhealthy diet, inactivity, tobacco use
Intermediate risk factors
Elevated BP, cholesterol, glucose
According to the CDC, _____ in 10 adults have a chronic disease
6
______ in 10 adults have 2 or more chronic disease
4
Examples of chronic disease:
heart disease
cancer
chronic lung disease
stroke
alzhimers’s
diabetes
chronic kidney disease
Good inflamation:
Acute, it kills of virus’s and stuff and helps us get over injuries, its a natural immune response, lasts 2-6 weeks
Bad inflamation:
its not fun when it doesn’t go away (chronic)
Signs of inflamation
SHRP
Swelling
Heat
Redness
Pain
What is the new blood pressure classification?
NORMAL: <120/<80
ELEVATED: 120-129/ <80
STAGE 1 HYPERTENSION: 130-139/ 80-89
STAGE 2 HYPERTENSION: >140/ >90
HYPERTENSION CRISIS: >180/ >120
What is the optimal Lipids level?
<100 mg/dl
What quantifies as a
<40 mg/dl
What is optimal Triglycerides level?
BELOW 150 mg/dl
What type of LDL you want, Pattern A or B?
YOU WANT A - large buoyant particles
YOU DON’T WANT B - more atherogenic
What does C-Reactive protein tell us?
Marker of inflammation
Low risk - 1.0 mg/L (less than 0.55 for me)
Moderate risk - between 1.0 and 3.0 mg
High risk - greater than 3.0 mg/L
How can we measure body composition?
BMI
Waist to hip ration
Body fat percentage, fat free mass
What is the overall probability that a man develops cancer?
1 in 2
What is the overall probability that a woman develops cancer?
1 in 3
What are the 3 most common cancers in men?
Prostate, lung and bronchus, and colon and rectum
What are the 3 most common cancers in women?
Breast, Lung and bronchus, and colon and rectum
Describe risk factors for Cancer:
Totally dependent on the type of cancer, however overall -
Tobacco use
Alcohol abuse
Age
Chronic inflammation
Diet
Hormones
Immunosuppression
Infections agents
Obesity
Radiation
Sunlight
What is the fundamental flaw of obesity research?
Bias and inaccuracies in self-reported studies
Describe doubly-labeled water:
Can be used to validate dietary intake if the following assumption is met - SEE BELOW
If body weight is stable or if weight change is known and body composition i known, changes in body energy may be accounted for
energy in = energy out
How does a doubly labeled water test work?
Subject consumes a quantity of water containing known concentrations of the stable isotopes
Differences between the elimination rates of the 2 isotopes relative to the body’s normal background levels estimates carbon dioxide production
Usually lasts 1-4 weeks
Advantages of doubly labeled water:
good estimation if in energy balance
no participant cooperation needed
free living environment
not reactive or intrusive
Disadvantages of doubly labeled water:
expensive
doesn’t determine day to day variations (because you’re staying in a study location or hospital)
Sophisticated and expensive analysis
Invalid for energy intake if weight is not stable or body composition not known
Doubly labeled water is the the ________ _______ for energy expenditure field measurement
gold standard
Who does the Department of Health and Human Services oversee?
CDC
FDA
NIH
What is precision nutrition?
Focuses on how we respond differently to food
What do we do with Precision nutrition (how do we use it)?
Develop more targeted and effective diet interventions based on an individuals personal characteristics
What is Nutritional Genomics (Nutrigenomics)?
Studies the effects of nutrition on the genome and regulation of gene expression
What is Nutritional Genetics (Nutrigenetics)?
Studies the effects of genetic variation on interaction between diet and disease, response to nutrients, or food bioactivities
What’s the difference between nutrigenomics and nutrigenetics?
Nutrigenomics focuses on the effects nutrients has on genes, while nutrigenetics focuses on the effects of genetic variation on nutrients
What is Epigenetics?
The study of how your behavior and environmental can cause changes that affect the way your genes work
What are DRI”s
Dietary refence intake
How are Daily Values different for DRI”s?
Nutrition labels
Daily Values = ______ + ________
RDI’s and DRV’s
What is considered a HIGH source on a food label?
20% or more of the DV
What is considered a GOOD source on the food label?
10-19% of the DV
What’s an EAR and what does it tell us?
Estimated Average Requirement
Average daily nutrient intake estimated to meet the requirements of half of the healthy individuals in a group
What’s an RDA and what does it tell us?
Recommended daily allowance
Average daily nutrient intake estimated to meet the requirements of nearly all (97%) of healthy people
What’s an AI?
Adequate intake
What’s an UL and what does it tell us?
Upper limit
Maximum daily intake unlikely to cause adverse health effects
An EAR is required to set an ________
RDA
Limitations of DRI’s
apply to a small group at a specific time
only as good as the science
nutrient absorption may be different in various regions of the world
complexity of relationship between diet and disease
What does AMDR stand for?
Acceptable macronutrient distribution range
What percent of your calories can come from carbs?
45-65%
What percent of your calories can come from fat?
20-35%
What percent of your calories can come from protein?
10-35%
What is the purpose of the dietary guidelines?
Designed for policymakers and nutrition and health professionals to help people consume healthy diets
Used to develop, implement, and evaluate federal food, nutrition, and health policies and programs
What are the main points of the 2020-2025 dietary guidelines?
Follow a healthy dietary pattern
Enjoy nutrient-dense food and beverage choices
Stay within calorie limits
Limit foods and beverages with higher added in sugars, saturated fats, and sodium
Limit alcohol intake
Describe MyPlate and its focuses
focus on whole fruits
vary your veggies
make ½ your grains whole grains
vary your protein routine
move to low-fat or fat-free dairy milk or yogurt
What is reductionism?
Refers to a focus on individual food compounds (eg protein, vitamins, antioxidants) as opposed to a holistic approach that focuses on food habits and the relationship between diet and health
Simplified version: taking one little part of something (like the center of wheat) and just eating that
What is a dietary pattern?
The quantities, proportions, variety, or combination of different foods, drinks, and nutrients in diet, and the frequency they are consumed at
Describe a western diet:
refined grains
red and processed meats
added sugars
high-fat dairy
Describe a prudent diet:
CAN’T/DOESN’T EAT
fried food
processed meats
sugar-sweetened beverages
eggs
added fat
Describe a lacto-ovo diet
Vegetarian, but can eat dairy and eggs
Describe a lacto diet:
Vegetarian, but can eat dairy products too
Describe an ovo diet:
Vegetarian, but can eat eggs
Describe a Pescatarian diet:
Vegetarian, but can eat fish
Describe a vegan diet:
No animal foods
What’s considered a very low calories diet
<800 kcal/day
What’s considered a low calories diet?
800 -1500 kcal/day
What’s considered a low fat diet?
<30% of kcal come from fat
Elements of food quality:
texture
flavor
nutritional content
ethical
sustainable production
local
Elements of a healthy diet:
Adequacy
Balance
Calorie control
Moderation
Variety
What makes a food organic?
No use of synthetic fertilizers, sewage sludge, irradiation, and genetic engineering
Is organic food healthier?
According to research, not really - it has very similar vitamin and mineral contents to non-organic foods
What is meant by calorie restiction?
Reducing average daily caloric intake below what is typical or habitual
What is the AMDR for fats/lipids?
20-35%
What is the overall idea of the Mediterranean diet?
Emphasis on vegetables, fruits, whole grains, beans, legumes
Includes low-fat or fat-free daily products, fish, poultry, non-tropical vegetable oils and nuts
Limits added sugars, sugary beverages, sodium highly processed foods, refined carbohydrates, saturated fats, and fatty or processed meats
What is the AMDR for carbohydrates?
45-65%
What is the DASH diet?
Dietary Approaches to Stop Hypertension
Similar to the food pyramid except the DASH diet recommends more fruits and vegetables
Used to reduce blood pressure
What is the AMDR for protein?
10-35%
Describe the Ketogenic Diet:
high-fat, moderate protein, low carb
adverse effects
nausea
vomiting
headache
fatigue
dizziness
insomnia
difficult to exercise tolerance
constipation
What is the %’s of fat, protein, and carbs you eat in Ketogenic diet?
55-60% fat
30-35% protein
5-10% carbohydrates
2000 kcal per day
What is the typical standard for identifying ultra-processed food?
5 or more processed ingredients used
What is an ultra-processed food?
Food made from industrial ingredients and additives, such as sugars, refined starches, fats, imitation flavors and colors, or industrial remnants, such as meat fats and scraps, with little or no whole food added
What is the definition for unprocessed foods?
Foods that are edible parts of plants (seeds, fruits, leaves, stems, etc.) or of an animal (muscle, eggs, milk, etc.), fungi, algae and water
What is the definition for minimally processed foods?
Foods that were once unprocessed, but have now been altered by processes such as removal of unwanted parts, drying, crushing, grinding, filtering, roasting, boiling, pasteurization, refrigeration, freezing, placing in containers, vacuum packaging, or non alcoholic fermentation. NONE OF THESE PROCESSES ADD SUBSTANCES SUCH AS SUGAR, SALT, OILS, OR FATS TO THE ORIGNIAL FOOD
Explain the Group 1 diet in NOVA
unprocessed or minimally processed foods
may occasionally include additives to preserve the properties of the original food
Explain the Group 2 diet in NOVA
processed culinary ingredients
these are substances obtained directly from group 1 or from nature by processes such as pressing, refining, grinding, milling, and spray drying
will add vitamins and minerals to group 1 foods (ex. salt, oil, sugar, etc.)
What designates a processed food?
2-3 additives
Explain the Group 3 diet in NOVA
processed foods, 2-3 additives
used to increase the durability of group 1 foods
fermented alcoholic drinks fall in this category
Explain the Group 4 diet in NOVA
ultra processed food and drinks
5+ additives
used to increase flavor, texture, preservation, etc.
can add vitamins, minerals, sugars, dyes, chemicals, etc.
What % of ultra processed foods comprise of our typical energy intake?
57.9%