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Genetic variation
Difference in alleles, phenotype or genotype among individuals in population
Mutations
Random changes in DNA sequences resulting in New alleles
recombination
Shuffles mutation to create new alleles
Why is genetic variation important?
It is required for all evolutionary change.
What are the 3 ways allele/genotype frequencies are measured?
Observable traits, protein electrophoresis, DNA sequencing.
What is evolution?
change of allele frequencies in a population over time
What is Hardy–Weinberg equilibrium?
under certain conditions, no evolution will happen
What are the 5 conditions for HWE?
No mutation, no migration, no natural selection, no genetic drift, no sexual selection
What happens to allele frequencies under HWE?
They remain constant across generations.
What does it mean if an allele is fixed?
its frequency is 1 (only allele in pop)
What does it mean for an allele to be lost
its frequency is 0 (allele dissapeears)
What are the 3 requirements for natural selection?
variation, heritability, best fit
How does natural selection affect allele frequencies?
avantageous alleles increase,
delterious alleles decrease
what leads to adaptation
Variation → Heritability → Selection → Adaptation
What is an adaptation?
A trait that increased fitness
directional stabilization
One extreme phenotype is favored;
one extreme over the other
What is stabilizing selection?
Intermediate phenotype favored;
selects against both extremes
What is disruptive selection?
Both extremes favored;
selects against intermediate
what is Genetic drift?
random changes in allele frequencies
what is the source of genetic variation
mutations and recombination
What is evolution by natural selection?
differential survival and reproduction based on heritable traits
non adadptive evolution
changes in allele frequencies not due to fitness
mutations
genetic drift
gene flow
alleles
diff versions of a gene
genotype
genetic makeup (aa, AA, Aa)
phenotype
physical traits