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Neurodevelopmental Disorders
Neurologically based disorders that are revealed in a clinically significant way during a child’s developing years
ADHD
Persistent pattern of inattention and/or hyperactivity-impulsivity interfering w/ functioning or development
At least 6 symptoms are required for either inattention or hyperactivity/impulsivity
Subtypes = Combined, predominantly inattentive, and predominantly hyperactive/impulsive
Biological Causes of ADHD (3)
Genetics = Runs in families, multiple genes related to dopamine are different in people w/ ADHD
Brain structure + function = Smaller brain volume, inactivity or abnormal brain function of frontal cortex or lobe, poor inhibitory control (endophenotype)
Toxins = Maternal smoking and food additives
Psychosocial Causes of ADHD (2)
ADHD children are often viewed negatively by others
Frequent negative feedback from peers and adults leads to social isolation and low self-esteem
Biological Treatment for ADHD (2)
Stimulant medications = Improve compliance and decrease negative behaviors
Non-stimulant medications = More limited efficacy
Psychosocial Treatment for ADHD (2)
Behavioral reinforcement = Increase appropriate behaviors and decrease inappropriate behaviors
Parent training
Specific Learning Disorder
Difficulty learning and using academic skills, w/ presence of symptoms for at least 6 months
Subtypes = Impairment w/ reading, written expression, or mathematics
Biological Causes of Specific Learning Disorders (2)
Disorders run in families, but subtypes do not
Subtle neurological difficulties (decreased functioning of areas responsible for word recognition)
Psychosocial Causes of Specific Learning Disorders
Specific languages may pose more challenges than others
Treatment for Specific Learning Disorders (3)
Specific skills instruction = Vocabulary, finding main idea
Strategy instruction = Decision-making, critical thinking
Direction instruction = Systematic w/ scripted lessons plans or teaching mastery by staying on topic to make sure child understands
Autism Spectrum Disorder (ASD)
Persistent deficits on social communication and interaction such social-emotional reciprocity, nonverbal communicative behaviors, and developing/maintaining relationships
Restricted repetitive patterns of behavior, interests, or activities (sameness)
Genetic Causes of ASD
Significant influence
Familial component = One child having it, chance of second child having it is 20%
Older biological parents associated w/ increased risk
Neurobiological Causes of ASD (2-3)
Larger amygdala = Elevated cortisol, anxiety, and fear
Oxytocin = Lower levels
Mercury in vaccines DO NOT increase risk, not supported
Psychosocial & Social Causes of ASD (2, Not Currently Supported)
Failed parenting (cold and perfectionistic)
Lack of self-awareness
Psychosocial/Behavioral Treatments of ASD (6)
Skill building
Reduce problem behaviors
Communication and language training
Increase socialization
Naturalistic teaching strategies
Early intervention
Biological Treatment of ASD
Typically ineffective
Drugs such as tranquilizers and SSRIs
Intellectual Developmental Disorder
Deficits in intellectual functions (reasoning, problem solving, planning, abstract thinking, etc.)
Deficits in adaptive functioning resulting in failure to meet developmental and sociocultural standards for personal independence and social responsibility
Onset of deficits during developmental period
Biological Causes of Intellectual Developmental Disorders (2)
Genetic = Lesch-Nyham syndrome, intellectual disability w/ symptoms of cerebral palsy and self-injurious behavior
Chromosomal = Down syndrome (extra 21st chromosome), most common cause of intellectual disability; Fragile X syndrome
Treatment of Intellectual Developmental Disorders (2)
Task analysis
Augmentative communication strategies
Prevention of Intellectual Developmental Disorders (2)
Early interventions such as Head Start
Prenatal interventions such as gene therapy
Psychological Disorder
Psychological dysfunction that is
Significantly distressing or impairing
Not typical or culturally expected
Including cognitive, behavioral, and emotional elements
Historical Conceptions (3)
Supernatural (demonic possessions), biological (physical illness), and psychological (Freud’s id, ego, superego; person-centered therapy; hierarchy of needs
1-Dimensional vs. Multi-Dimensional Models
o 1-dimensional = Single cause that ignores information from other areas (OCD = Family history)
o Multi-dimensional = “System”/multiple of influences drawn upon from several sources
Diathesis-Stress Model
Biological vulnerability + environmental stressors = Increased likelihood of disorder.
Stigma’s Impact
Limits the degree to which people express mental health and seek treatment
Equifinality
Many paths to 1 outcome
Multifinality
Many outcomes come from 1 source
Assessment vs. Diagnosis
A= Evaluation and measurement of multi-dimensional factors
D = How symptoms fit diagnostic criteria (interpretation)
Mental Status Exam
Measure appearance (clothing and hygiene), behavior, thought processes, mood/affect (happy, blunt, sad), intellectual function, and sensorium (know what year it is) of patient
Psychological Testing (3)
Projective = Analyzing unconscious processes and projecting personality aspects onto ambiguous test stimuli
Personality = Objective tests such as the MMPI (567 items with true/false questions that discern people with or without psychological disorders)
Intelligence = School performance and intellectual functioning/IQ (ex. Deviation IQ)
DSM vs. ICD
DSM published and updated by American Psychiatric Association (APA)
ICD published by WHO covering medical conditions
Dates of DSM Editions (3)
DSM-III = 1980
DSM-IV = 1994
DSM-5 = 2013
Generalized Anxiety Disorder
Excessive anxiety and worry occurring for numerous events, not just extremely stressful ones
Panic Disorder
Recurrent unexpected panic attacks w/ intense fear/discomfort, sweating, heart palpitations, chest pain, dizziness, etc.
Persistent concern or worry of future panic attacks, and maladaptive change to behavior to avoid them
Agoraphobia
Fear or anxiety of particular places or situations (transport, open spaces, outside of the home alone)
Individual fears or avoids situations
Fear/anxiety out of proportion to actual danger
Fears avoided and endured w/ stress
Specific Phobia
Fear or anxiety about a specific object or situation (ex. Flying, heights, animals, injections, blood)
Phobic object/situation provokes immediate fear or anxiety
Fear/anxiety out of proportion to actual danger
Social Anxiety Disorder
Fear or anxiety about 1 or more social situations in which individual is exposed to possible scrutiny from others (social interactions, performing)
Fears avoided and endured w/ stress
Fear/anxiety out of proportion to actual danger
PTSD
Person was exposed to death, threatened death, actual or threatened serious injury, or actual or threatened sexual violence
Traumatic event is persistently re-experienced through nightmares, flashbacks, emotional reactivity, and distress
Avoidance of trauma-related stimuli after the trauma
Adjustment Disorder
Anxious or depressive reactions to life stressors such as moving, new job, divorce, etc.
OCD
Obsessions = Recurrent, persistent, intrusive, and unwanted thoughts causing anxiety and stress and thus attempts to ignore them by other thoughts and/or actions
Compulsions = Repetitive mental thoughts or behaviors performed to curb obsession and prevent anxiety and stress
Body Dysmorphic Disorder
Preoccupation with some imagined defect in appearance—even if there is an actual defect, it appears slight to others
Hoarding
Excessively collecting and keeping items with minimal value, leading to cluttering and disruption of living space
Trichotillomania
Urge to pull out one’s own hair from anywhere on the body
Leads to noticeable hair loss on scalp, eyebrows, arms, pubic region, etc.
Excoriation
Repetitive and compulsive picking of the skin, leading to tissue damage
Face is common target
Major Depressive Episode
Depressed mood and diminished interest or pleasure in activities
Most of the day, nearly every day, for at least 2 weeks
Manic Episode
Inflated self-esteem (grandiosity), more talkative, and/or flight/racing of ideas
At least 1 per week
Hypomanic Episode
Shorter, less severe version of manic episodes
Last at least 4 days
Major Depressive Disorder
1 or more major depressive episodes w/ periods of remission for at least 2 weeks
Never had a manic or hypomanic episode
Persistent Depressive Disorder
Depressed mood for most of the day, for more days than not, for at least 2 years
Never been w/out symptoms for more than 2 months at a time in 2-year period
Never been a manic or hypomanic episode, along w/ never meeting criteria for cyclothymic disorder
Other possible symptoms = Poor appetite/overeating, low self-esteem, and feelings of hopelessness
Diagnostic Specifiers
Additional diagnostic label for clinicians to convey extra symptom information
Not mandatory—only assigned when appropriate
Bipolar I Disorder
Alternations between major depressive and manic (2 week) episodes
Cyclothymic Disorder
Alternating between less severe depressive and hypomanic symptoms
No criteria met for major depressive, manic, or hypomanic episodes
“Mild” version of bipolar II
Bipolar Specifier: Rapid Cycling
Moving quickly in and out of mania and depression
Associated w/ greater severity
Gender Differences w/ Suicide
Males complete more suicides
Females attempt suicide more
Disparity due to males using more lethal methods
Prevention of Suicide (Professional and Non-Professional)
Professional = Risk assessment (ideation, plans, intent, means, etc.), develop safety plan (who to call, coping strategies), and sign no-suicide contract
Non-Professional = Talk to them and ensure they’re getting support; remove lethal methods
Biological Causes for Mood Disorders & Suicide (2)
Genetics play a strong contribution
Neurobiological = Serotonin regulates norepinephrine and dopamine, and mood disorders are related to low levels of serotonin
Psychological Causes for Mood Disorders & Suicide (3)
Learned helplessness = Lack of perceived control over life events leads to decreased attempts to improve own situation
Attributional Style = Internal (my fault), stable (future ones are my fault), global (everything is bad)
Cognitive errors = Arbitrary inference (more negative aspects) and overgeneralization
Social/Cultural Causes for Mood Disorders & Suicide
Lack of social support predicts late onset of depression
Treatment of Mood Disorders: Antidepressants (4) and Mood Stabilizers (1)
Only 50% benefit
SSRI’s = Block reuptake of serotonin
Tricyclic antidepressants = Block reuptake of norepinephrine
Monoamine oxidase inhibitors = Block monoamine oxidase
Mixed reuptake inhibitors = Block reuptake of serotonin and norepinephrine
Lithium = Mood stabilizer for depressive and manic symptoms of bipolar
Treatment of Mood Disorders: ECT + TMS
Electroconvulsive Therapy = Brief electrical current applies to brain that creates temporary seizures
Transcranial Magnetic Stimulation = Magnets to generate precise localized electromagnetic pulse, less effective than ECT
Treatment of Mood Disorders: Psychosocial
CBT = Cognitive errors of thinking
Tolerance
Needing more of a substance to get the same/reduced effects from the same amount
Withdrawal
Physical symptom reaction when substance is discontinued after regular use
Major Classes of Substances (4)
Depressants = Alcohol effects, delirium tremens, dementia, and Wernicke-Korsakoff disorder (confusion, lack of coordination, impaired speech)
Stimulants = Increased alertness and energy
Opioids = Narcotic effects
Hallucinogens = Altered sensory perceptions w/ delusions and paranoia
Biological Causes of Substance-Related Disorders
Multiple genes
Genetic differences in alcohol metabolism impact which drugs are most effective for treating disorders
Psychological Causes of Substance-Related Disorders
Opponent-process theory = Drugs are easiest way to alleviate feelings of withdrawal (good, then bad, cycle continues)
Cognitive Causes of Substance-Related Disorders (2)
Expectancy effects = Use drugs when anticipating positive effects
Cravings = Triggered cues like mood, environment, availability of drug
Biological Treatment for Substance Abuse (3)
Agonist = Use similar drug to abused drug
Antagonistic = Block or counteract positive effects
Aversive = Makes use of substance extremely unpleasant
Psychosocial Treatment for Substance Abuse: Community Support Programs
Treating addiction as a disease
Goal of abstinence
Social support
Non-Substance Disorders Related to Addiction
Some disorders exist (gambling, explosive, pyromania, etc.)
Follow addictive, compulsive patterns regarding a behavior rather than substance
Somatic Symptom Disorder
1+ somatic symptoms (excessive/maladaptive response to health concerns) that are distressing and/or result in significant disruption of daily life
Excessive thoughts, feelings, and behaviors related to it
Illness Anxiety Disorder
Fears of having/acquiring illness
Somatic symptoms not present; or if present, only mild in intensity
Excessive health-related behaviors (checking for signs) or maladaptive avoidance of Dr.’s or hospitals
Causes of Somatic Symptom/Illness Anxiety (2)
Heightened attention to physical sensations
Benefits of attention and sympathy
Treatment of Somatic Symptom/Illness Anxiety
CBT - Especially for Illness Anxiety
Reduce secondary gains
Conversion Disorder (Functional Neurological Symptom Disorder)
1+ symptoms of altered voluntary motor or sensory function
Incompatibility between symptom and recognized neurological or medical conditions
Treatment for Functional Neurological Symptom Disorder (3)
Process trauma or treat posttraumatic symptoms
Remove sources of secondary gain
Factitious Disorders
Purposely faking physical symptoms to be in “sick role”
Munchausen syndrome = Factitious disorder imposed by proxy (ex. Caregiver inducing symptoms on child)
Depersonalization-Derealization Disorder
Persistent or recurrent experiences of unreality or detachment from self (depersonalization) and surroundings (derealization)
Reality testing remains intact
Dissociative Amnesia
Not able to recall memories of self (localized to specific event/events or generalized w/ identity and life history)
Dissociative Identity Disorder
Disruption of identity by 2+ personality states w/ different affects, behaviors, memories, perception, etc.
Recurrent gaps in recall of everyday events, personal info, and/or traumatic events
Not normal part of broadly accepted cultural or religious practice
Cause = Childhood trauma/abuse
Bulimia Nervosa
Recurrent episodes of binge eating for a discrete (2-hour) period
Lack of control overeating during episode
Anorexia Nervosa
Restriction of eating/energy intake leading to significantly low body weight
Intense fear of gaining weight or becoming fat
Disturbance of how one’s body weight or shape is evaluated
Binge-Eating Disorder
Recurrent episodes of binge eating large amounts of food and finding loss of control
Episodes related to eating faster, feeling uncomfortably full, not feeling hungry, eating alone, and feelings of disgusted
Disturbance not occurring during episodes of anorexia and w/out bulimia nervosa
Causes of Eating Disorders (3-4)
Social = Media attributing thinness w/ success, dietary restraint, family who is heigh achieving and cautious of external appearances
Biological = Genetic component
Psychological = Sense of control
Perfectionism
Treatments for Eating Disorders
Antidepressants (not for anorexia)
Family treatment (anorexia only)
Insomnia
Difficulties initiating and maintaining sleep
Early-morning awakening and not being able to go back to sleep
At least 3 nights per week and/or for at least 3 months
Treatment for Insomnia
CBT for insomnia, including psychoeducation, changing beliefs about sleep, and keeping up with a sleep diary
Relaxation and stress reduction, modifying unrealistic expectations about sleep
Sleep hygiene - Make bedroom a place for sleep
Hypersomnolence
Excessive sleepiness (sleeping during the day or more than 9 hours) despite sleeping 7 hours
Difficulty being fully awake
At least 3 times per week for at least 3 months
Narcolepsy
Recurrent periods of irrepressible need to sleep, passing into sleep, or napping occurring within the same day
3 times per week for the past 3 months
Circadian Rhythm Sleep
Affects melatonin production and sense of night and day
Causes = Shift in work type (irregular hours), familial type/history, and delayed/advanced sleep phase (biological clock “set” earlier or later than normal bedtime)
Nightmare Disorder
Repeated occurrences of extended, extremely dysphoric, and well-remembered dreams that involve avoiding threats to survival, security, or physical integrity
Occur during second half of major sleep episode
On awakening, person rapidly becomes oriented and alert
REM Sleep Behavior Disorder
Repeated episodes of arousal during sleep associated w/ vocalization and/or complex motor behaviors
Upon awakening, individual is completely awake, alert, and not confused or disoriented
Psychological Causes of Dysfunctions (2)
Anxiety and negative thoughts about encounters
Avoid awareness of cues
Social and Cultural Causes of Dysfunctions (3)
Unpleasant or traumatic experiences
Poor interpersonal relationships
Lack of communication
Treatment of Dysfunctions
Psychoeducation alone can be surprisingly effective
Sensate focus + nondemand pleasuring = Focus on sensations w/out trying to achieve orgasm to decrease performance anxiety
Paraphilic Disorders
Misplaced attraction and arousal to inappropriate people/objects
Includes: Fetishistic, voyeuristic, exhibitionistic, frotteuristic, transvestic, sexual sadism, sexual masochism, and pedophilic
Gender Dysphoria and Causes
Marked incongruence between one’s experienced/expressed gender and assigned gender (trapped in the wrong body)
Genetic component
Prenatal = Exposure to certain hormones in womb (higher levels of testosterone may masculinize female fetus)
Personality Disorders
Persistent pattern of emotions, cognitions, and behavior leading to emotional distress to person affected and/or others causing difficult work and relationships
Cluster A and Disorders (3)
Odd/eccentric
Paranoid (unreasonable suspicion and mistrust of others), schizoid (cold, aloof, distant), and schizotypal (magical and unusual thinking and dress)
Cluster B and Disorders (4)
Dramatic/erratic
Antisocial (do not comply w/ social norms and rights of others, impulsive, deceitful, lacking empathy), borderline (personality disorder w/ mood disorder), histrionic (overly sensational and sexual, center of attention), and narcissistic (exaggerated and unreasonable sense of self-important)