immunosero

1. Reaction slide in CRP and RF

6-cell agglutination slide

2. Director/orchestrator of immune response

T helper cells

3. Detects cross-reactive ab in primary atypical pneumonia

Strep MG agglutination test

4. Most potent anaphylatoxin

C5a

5. Anti-streptolysin O tube is based on hemolytic activity of

Streptolysin O

6. All seen in secondary stage of Sy

Condylomata lata, reactive regain test, generalized rash Except: gummas

7. Most common cause of neonatal abnormality

Human herpes virus 2

8. Ig treated with papain results to cleavage in

2 Fab + 1 Fc

9. Most potent IgG class in complement

IgG3

10. SLE is defined by presence of LE cell while the presence of Downey cells are an infection with

EBV

11. Chemical groups that could bind ab but incapable of stimulating formation unless bound to a larger carrier molecule

Hapten

12. True neonatal infection is defined by

IgM

13. Specificity of the ab-combining site is conferred upon by

Amino acid sequence of the VL and VH chains

14. Febrile Ab are generally detected in

RF Except: Typhoid fever, Typhus, Tularemia, Brucellosis

15. Type 1 hypersensitivity is mediated by

IgE

16. Ag used in VDRL consists of

Cardiolipin with cholesterol - lecithin

17. The typhidot method for typhoid fever dx makes use of labelled

Salmonella antigen

18. Which of the ff is the preferred cell type for HLA typing

Lymphocytes

19. Below pH 8.3, Ab bear a slightly positive charge that will result in their electrophoresis migration towards the

Cathode

20. The majority of circulating lymphocytes in the peripheral blood are

T cells

21. Neonates born to HBsAg+ mothers are best protected by

Passive immunization

22. Louis Pasteur developed vaccines against

Chicken cholera, Anthrax, Rabies

23. Most immunogenic

Proteins

24. Inflammation involves all of the following processes

Smooth muscle contraction migration of phagocytic cells increased blood supply to the affected area increased leukocyte adhesion Except: decreased capillary permeability

25. Specific biologic fxn of ab is dictated by

Fc fragment

26. Product of humoral immune response is directed by

Plasma cells

27. Corresponding dilution of a 0.04 mL serum in Widal slide test is

1:40

28. The most preferred vein for venipuncture in the antecubital fossa is

Median cubital

29. Ag titration is otherwise known as

Alpha procedure

30. Mature lymphocytes are found in this part of the thymus

Medulla

31. Proteus spp. used in Weil-Felix test

detect anti-Rickettsial ab

32. In a competitive ELISA mx, the intensity of the colored product is related to the amt of analyte. A deep colored product means

Less amt of analyte

33. A landscape of mountain shaped precipitate peaks is seen in

Ressler mx

34. Paratope refers to

Ab-combining site

35. Immobolized ab contained in a gel tube is a method by

Oudin

36. Ig classes are reffered to as

Isotypes

37. The ff are wandering phagocytic cells except

Osteoblasts

38. Class I-MHC molecules are recognized by

CD8 cells

39. The chemical name for cardiolipin

Diphosphatidyl glycerol

40. Most striking feature of dse is presence of wolf's head-like rash in the cheek area

SLE

41. Phagocyte dysfxn occurs only in the male population

Congenital dysphagocytosis

42. Lambda light chain is determined in chromosome #

22

43. The autoab assoc with infectious mononucleosis is

Anti-i

44. He is considered the Father of Immunology

Jenner

45. Presumptive test applied for the dx of IM

Paul-Bunnel

46. A hemolysin was also previously known as

Amboceptor

47. The ff are blood-borne dses

Hep B, Hep C, Hep D Except: Hep A

48. GVHR is due to

Immunosuppressed host

49. Major sites of lymphopoiesis include

Thymus, BM Except: Spleen, LN, MALT

50. Absence of thymus due to embryologic underdevelopment is called

DiGeorge syndrome

51. Person/s responsible for coining 'anamnesis'

Wassermann and Von Dugern

52. Typhoid fever is found very early in

Blood

53. Latex reagent in RF consists of

IgG coated unto latex

54. Naked virus

HDV

55. Significant degree of agglutination when getting ab titer

+2

56. Cold hemagglutinin test detects presence of cold autoantibody in m. pneumoniae infx

Anti-I

57. Infection of CD8 cells is characteristic of

CMV

58. Detection of ag in tissues is achieved by employing this method

Direct immunofluorescence

59. CEA is seen in adult patients suffering from

Adenocarcinoma

60. In electrophoresis, the antigen is usually loaded unto the

Cathode

61. The best serologic method to diagnose neurosyphilis

VDRL

62. The cytotoxic type of hypersensitivity is mediated mainly by

IgG

63. The most common neoplasm found in AIDS

Kaposi's sarcoma

64. This inhibits complement activity by binding to C5b67 membrane receptors of cells

S protein

65. EBV can infect B cells through this marker

CD21

66. Brill-Zinsser disease is caused by

R. prowazekii

67. This test involves the simplification of DNA sequences before subsequent detection

PCR

68. Enzyme immunoassays employing a separation step are called _ assays

Heterogenous

69. A longer latent period is seen in

Primary immune response

70. It is also referred to as genito-herpes

HSV-2

71. Infection is brought about by reactivation of chickenpox

VZV

72. Single diffusion, double dimension

Mancini

73. The best immunogens are ___ in nature

Proteins

74. In electrophoresis, cathode means

Negatively-charged area

75. The component of RPR antigen which neutralizes the anticomplementary action of cardiolipin

LECITHIN

76. These salmonella antibodies produce large, flaky,loose aggregates when reacted with homogenous Ags

Salmo H

77. In the CRP, latex test, the substance in the patients serum acts as

agglutinogen

78. In ASTO determination by hemolysis-inhibition, one should not test a serum sample that is

lipemic, hemolyzed, bacterially contaminated.

79. "C" in CRP means

Capsule

80. Nature of reactants in precipitation

soluble Ag & Ab

81. A true negative result in lytic complement fixation test will result to

No lysis

82. Passive hemagglutination has this analyte

Anti-HBs

83. Activated by the presence of mannose expressed on the surface of microorganism

Mannan-binding

84. Binding of C1q on CH3 of Ag-bound IgM

Classical

85. Formation of the membrane attack complex (MAC)

ALL (Classical, Alternative, Mannan-binding)

86. C5 convertase (C4b2a3b)

Classical

87. Activated through "tickover activation"

Alternative

88. Radioimmunoassay

Primary reaction

89. Elek's test

Secondary Reaction

90. Hemagglutination-inhibition tests

Secondary reaction

91. Immunofluorescence tests

Primary reaction

92. Major lymphocyte in germinal center

B cells

93. Component of cutaneous immune system that expresses class II MHC

LANGERHANS

94. Molecule produced by NK cells in mediated killing?

GRANZYME, PERFORIN

95. Ig produced on surface of B cells

IgM and IgG

96. Counterpart of rocket electrophoresis

Oudin

97. Reverse passive agglutination determines

Ag

98. Immobilized ab in a gel

Oudin (single, single)

99. Cardiolipin is otherwise known as

Wasserman ag

100. Particle in latex agglutination test of RA

IgG on latex