Systemic Lupus Erythematosus (SLE) Overview

These flashcards cover essential vocabulary related to the pathophysiology, symptoms, and treatments of systemic lupus erythematosus (SLE).

Serositis

Inflammation of the pleura or pericardium.

Lupus Nephritis

A renal disorder characterized by inflammation related to systemic lupus erythematosus.

Photosensitivity

Skin rashes that occur upon exposure to sunlight, commonly associated with lupus.

Malar Rash

A butterfly-shaped rash located across the cheeks and nasal bridge, characteristic of lupus.

Antiphospholipid Antibodies

Autoantibodies that can increase the risk of thrombosis and are often present in patients with lupus.

Hematological Disorders

Conditions affecting blood components, which can be associated with lupus.

Discoid Rash

Red raised patches on the skin typically associated with lupus.

Class IV Lupus Nephritis

Diffuse proliferative lupus nephritis that carries the worst prognosis.

Autoantibodies

Antibodies that target the body's own cells, significant in the diagnosis of autoimmune diseases like lupus.

Alopecia

Hair loss that can occur in lupus patients, sometimes as a result of the disease itself.

Immunosuppressants

Medications used to decrease the immune response, often prescribed for lupus treatment.

Anorexia

Loss of appetite, which can be a subjective complaint of lupus patients.

Thrombosis

The formation of a blood clot inside a blood vessel, which can be linked to antiphospholipid syndrome in lupus patients.

Proteinuria

The presence of excess proteins in urine, a sign of kidney involvement in lupus.

Corticosteroids

Anti-inflammatory medications often used as first-line treatment in lupus.

Raynaud's Phenomenon

Vascular condition causing discoloration of the fingers or toes in response to cold or stress, seen in lupus patients.