Cellular Respiration Regulation

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Last updated 4:17 AM on 4/10/26
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5 Terms

1
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ATP inhibits:

  • PFK-1 (allosteric)

  • PDH

  • citrate synthase

  • isocitrate dehydrogenase

  • a-ketoglutarate dehydrogenase (also GTP)

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NADH inhibits:

  • PDH

  • citrate synthase

  • isocitrate dehydrogenase

  • a-ketoglutarate dehydrogenase

3
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enzymes inhibited by their products

  • PFK-1 by citrate (allosteric)

  • hexokinase by glucose-6-phosphate

  • PDH by acetyl CoA

  • a-ketoglutarate dehydrogenase by succinyl-CoA

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enzymes with energy signal activators

  • PDH (ADP + pyruvate)

  • isocitrate dehydrogenase (ADP + Ca2+)

  • PFK-1 (AMP + ADP)

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PDH covalent modification regulators

  • inhibited by phosphorylation

  • activated by dephosphorylation