Intracellular Accumulations and Extracellular Depositions

These flashcards cover key vocabulary related to intracellular and extracellular accumulations and depositions as discussed in the lecture.

Intracellular accumulations

Deposits within cells that may be harmless or indicate injury.

Extracellular depositions

Deposits outside of cells that can be associated with tissue injury.

Fatty change

Accumulation of excess triglycerides in parenchymal cells, notably in the liver.

Hyaline change

Intracellular or extracellular accumulation of proteins leading to a glassy appearance.

Anthracosis

Black pigmentation of the lung due to accumulation of inhaled carbon.

Lipofuscin

A yellowish-brown pigment that increases with senility and starvation.

Hemosiderin

Brownish pigment formed from the breakdown of hemoglobin, associated with iron overload.

Pathological calcification

Deposition of calcium salts in tissues other than bone and teeth.

Amyloidosis

Extracellular deposition of abnormal proteins known as amyloid, characterized by specific staining properties.

Signet ring appearance

A characteristic morphology in fatty change where large fat vacuoles displace the nucleus eccentrically.