Nucleotides and Protein Metabolism Review

Practice flashcards covering de novo nucleotide synthesis, protein requirements, proteolytic enzymes, and metabolic markers based on lecture notes.

Deamination of adenine gives __________.

Inosine

Inosine is a product of __________ and __________.

AMP deamination and adenosine deamination

Allosteric site is a regulatory site on __________ or __________.

Enzyme or protein

Metabolic precursors of the De novo synthesis of nucleotides are __________ and __________.

Amino acids and $\text{ribose 5-phosphate}$

The major site of purine synthesis is __________.

Liver

The synthesis of phosphoribosyl pyrophosphate from __________ requires phosphoribosyl pyrophosphate synthetase.

$$\text{ribose 5-phosphate}$$

__________ is the metabolic precursor required for the conversion of $5\text{-phosphoribosylamine}$ to $5\text{-phosphoribosyl glycinamide}$ in the De novo synthesis of purine nucleotide.

Glycine

__________ can be used to induce parturition.

$PGE_2$ and $PGF_2$

Is arachidonic acid a saturated fatty acid? __________.

No

Proteins are primary body constituents and they are either __________ or __________.

Structural or functional

An adult requires a range of __________ grams of protein per day.

$70$ to $100$

The carbon skeletons of amino acids can be oxidized to __________.

Yield energy

Proteolytic enzymes are produced in the __________, __________, and __________.

Stomach, pancreas, and small intestine

The secretion of secretin into the blood is triggered by __________.

Movement of acidic stomach contents into the small intestine

Secretin stimulates the pancreas to secrete __________.

Bicarbonate

The absorption of most amino acids into the intestinal mucosal cells involves __________.

An active transport mechanism

The primary role of amino acids is to serve as __________.

Building blocks for synthesis of tissue protein

The excess amino acids in the body cannot be __________ nor __________.

Stored nor excreted

The enzyme that catalyzes the conversion of $\text{fructose-6-phosphate}$ to $\text{fructose-1,6-bisphosphate}$ is __________.

Phosphofructokinase-I

The only water-soluble and freely diffusible cytochrome in the electron transport chain is __________.

Cytochrome c

The synthesis of liver glucokinase decreases in response to pancreatic hormone __________.

Glucagon