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Functions of digestive system
1) Ingestion
2) Mechanical processing —> Crushing/shearing, propulsion
3) Digestion —> Enzymes/chemical rxns
4) Secretion —> Release water, acids, buffers, mucus, enzymes into lumen
5) Absorption —> (lumen to capillaries/lymphatic vessels) of organic molecules, electrolytes, vitamins, minerals, water
6) Excretion —> Defecation, egestion
Peritoneum
Superficial mesothelium covering a layer of areolar tissue
Visceral peritoneum
Serosa/Adventitia —> Covers organs
Parietal peritoneum
Lines the inner surfaces of the body cavity
Peritoneal cavity
Potential space containing a bit of serous fluid
Peritoneal fluid
Produced by serous membrane lining
Reduces friction between serous lining
7 lit. produced/absorbed daily
Ascites
Abdominal swelling due to build up of peritoneal fluid
Mesenteries
Double layers of peritoneal membranes (serous membranes) that connect parietal & visceral peritoneum
Mesentery functions
1) Support & stabilize organs in abdominopelvic cavity
2) Provide a route for associated blood/lymphatic vessels/nerves
3) Prevent intestines from becoming entangled
Retro-peritoneal
Organs that connect to the back of abdominal cavity by a muscular wall but not a mesentery
Ex: Kidneys, pancreas, rectum, duodenum
Embryonic development
Digestive tract/accessory organs suspended in peritoneal cavity
By Dorsal/Ventral mesentery
What disappears along most of the digestive tract later after embryonic development?
Ventral mesentery
Persists in adults only as lesser omentum & falciform ligament
From ventral mesentery
Falciform (connects diaphragm to liver)
Lesser omentum (liver to medial side of stomach)
From dorsal mesentery
Greater omentum (lateral side of stomach)
Mesentery proper (Sheet associated with small intestine, suspends all but the first 25 cm)
Mesocolon (mesentery associated with large intestine)
Histology (inner to outer)
Mucosa
Submucosa
Muscularis externa
Serosa (adventitia in special areas)
Mucosa parts
Epithelium —> stratified squamous & simple columnar
Plicae
Villi
Lamina propria
Muscularis mucosa
Mucosa Epithelium
Stratified squamous epithelium —> Oral cavity to esophagus/anus
Simple columnar —> Stomach, both intestines
Life span = 2-6 days
Mucosa Lamina propria
Contain small blood vessels & mucous glands
Mucosa Muscularis mucosa
Smooth muscle —> junction between mucosa & submucosa
Submucosa
Large blood/lymphatic vessels
Submucosal plexus
Submucosal plexus
AKA Plexus of Meissner
Sympathetic & parasympathetic nerves with sensory neurons
Muscularis externa
Dominated by smooth muscles (peristalsis)
Myenteric plexus (symp & parasymp ganglia, neurons)
Parasympathetic stimulated = (+) muscle tone, contraction & peristalsis
Serosa
AKA visceral peritoneum
Outer membrane of organ
ALL GI tract except (oral cavity, pharynx, esophagus, & rectum = adventitia collagen fibers)
Myenteric plexus function
Controls circular & longitudinal muscle contraction
Sensory/motor neurons