ETC Complexes

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Last updated 9:17 PM on 4/8/26
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9 Terms

1
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Complex I

NADH Q Oxidoreductase: NADH/NAD+ —→ FMN/FMNH2 —→ 4 Fe/S clusters —→ Q/QH2 (ubiquinone to ubiquinol)

2
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How many H+ pumped in Complex I?

4 from matrix into IMS

3
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Complex II

Succinate Q Reductase: Succinate/Fumarate (oxidation) —→ FAD/FADH2 —→ 2 Fe/S clusters —→ Q/QH2

4
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How many H+ pumped in Complex II?

0

5
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Complex III

QH2 Cytochrome c Oxidoreductase: QH2 —→ Fe/S cluster —→ heme c1 —→ heme c (Cytochrome c) OR QH2 —→ heme b —→ heme c (Cytochrome c)

6
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How mant H+ pumped in Complex III

4; 2 from matrix to IMS and 2 from QH2 to IMS

7
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Complex IV

Cytochrome c Oxidase: (2) Cytochrome c —→ Copper unit a —→ heme a —→ heme a3 —→ Copper unit b —→ O2 OR (2) Cytochrome c —→ (2) H20

8
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How many H+ pumped in Complex IV?

2 from matrix into IMS (if you use 2 Cyt c)

9
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Exam Style Q

  1. 2 ATP from glycolysis and 2 ATP from Krebs

  1. Malate/aspartate shuttle (h, k, and l) = 2 NADH x 2.5 ATP V.S. Glycerol 3 phosphate shuttle (m and b) = 2 NADH x 1.5 ATP

  1. Glycolysis = 2 NADH x 2.5 ATP

  1. PDC = 2 NADH x 2.5 ATP

  1. Krebs = 6 NADH x 2.5 ATP and 2 FADH2 × 1.5 ATP

Total = 32 or 30 depending on Step 2